Tiny endoscopic optical coherence tomography probe driven by a miniaturized hollow ultrasonic motor

Area of Science:

• Biomedical Engineering
• Optical Imaging
• Medical Devices

Background:

• Optical coherence tomography (OCT) is a valuable non-invasive imaging technique.
• Existing endoscopic OCT probes often face limitations in size and scanning capabilities.
• Miniaturization and improved scanning are crucial for advanced endoscopic diagnostics.

Purpose of the Study:

• To develop an ultra-small, motorized endoscopic probe for 360-degree circumferential scanning OCT.
• To enhance imaging resolution and sensitivity for in-situ tissue analysis.

Main Methods:

• Integration of a miniaturized hollow ultrasonic motor for objective lens rotation.
• Utilization of a customized aspheric right-angle lens to increase numerical aperture.
• Development of a 1.5 mm outer diameter probe with an internal fiber channel.

Main Results:

• Achieved 360-degree unobstructed circumferential scanning.
• Demonstrated spectral-domain OCT imaging of biological tissue and a phantom.
• Obtained high transverse resolution (6.6 μm lateral) and axial resolution (7.5 μm axial).
• Reached a sensitivity of 96 dB.

Conclusions:

• The developed ultra-small endoscopic OCT probe offers superior maneuverability and imaging performance.
• This technology has the potential to significantly advance minimally invasive endoscopic diagnostics.
• The probe's design overcomes previous limitations in size and field of view for endoscopic OCT.