Related Experiment Video
Updated: May 8, 2026

Correlative Confocal and 3D Electron Microscopy of a Specific Sensory Cell
Published on: July 19, 2015
Recent progress in research on the distribution and function of NUCB2/nesfatin-1 in peripheral tissues
Xun Cao1, Xiao-Min Liu, Li-Hong Zhou
1Department of Endocrinology, Harbin Medical University, Harbin 150001, China.
Abstract:
Nesfatin-1 is a polypeptide derived from the posttranslational processing of the N-terminal fragment of nucleobindin 2 (NUCB2), that was originally identified as an anorexigenic hypothalamic neuropeptide. A number of reports have recently shown that NUCB2/nesfatin-1 is widely expressed in various peripheral tissues, including those of the gastrointestinal tract where it may participate in various pathophysiological processes. One of its roles may be regulation of energy homeostasis. As a result, nesfatin-1 may be a novel target for exploring the underlying mechanisms and the treatment of metabolic syndromes.
Related Concept Videos
NF-κB-dependent Signaling Pathway
NF-κB-dependent Signaling Mechanism
The heterodimer of NF-κB...
The Nucleolus
Regulation of Nuclear Protein Sorting
Regulation of Food Intake
