First clinical manifestation of Brugada syndrome during pregnancy

Dirk Prochnau1, Hans R Figulla, Ralf Surber

  • 1Department of Internal Medicine I, Jena University Hospital, Erlanger Allee 101, 07747, Jena, Germany. dirk.prochnau@med.uni-jena.de

The role of hormonal changes during pregnancy in Brugada syndrome is unknown. Only rare case reports of Brugada syndrome during pregnancy have been published. In this article, we describe a patient with first clinical manifestation of Brugada syndrome during pregnancy. The definitive diagnosis could only be achieved by drug challenge with ajmaline after childbirth because the spontaneous typical Brugada-like pattern was absent. Elevated hormone levels during pregnancy may increase the risk for arrhythmias in particular cases.

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