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Updated: May 8, 2026

Evaluation of Left Ventricular Structure and Function using 3D Echocardiography
Published on: October 28, 2020
[Comparative evaluation of left ventricular function by two-dimensional echocardiography and three-dimensional
Anita Kalapos1, Péter Domsik, Tamás Forster
1Szegedi Tudományegyetem, Általános Orvostudományi Kar, Szent-Györgyi Albert Klinikai Központ II. Belgyógyászati Klinika és Kardiológiai Központ Szeged Korányi fasor 6. 6720.
Insights
Left ventricular dysfunction is severe in noncompaction cardiomyopathy patients. Three-dimensional speckle-tracking echocardiography revealed reduced strain and absent left ventricular twist, indicating impaired contractility.
Area of Science:
- Cardiology
- Medical Imaging
- Echocardiography
Background:
- Noncompaction cardiomyopathy is characterized by incomplete myocardial compaction, leading to impaired left ventricular function.
- Understanding the extent of left ventricular dysfunction is crucial for managing noncompaction cardiomyopathy.
Purpose of the Study:
- To comparatively evaluate left ventricular dysfunction in noncompaction cardiomyopathy patients.
- To assess the utility of 2D echocardiography and 3D speckle-tracking echocardiography in characterizing left ventricular dysfunction.
Main Methods:
- Study included 7 patients with noncompaction cardiomyopathy and 10 healthy controls.
- Both groups underwent 2D echocardiography and 3D speckle-tracking echocardiography.
- Left ventricular volumes, ejection fraction, strain, and rotation parameters were analyzed.
Main Results:
- Noncompaction cardiomyopathy patients exhibited increased LV volumes and reduced ejection fraction compared to controls.
- All 3D speckle-tracking echocardiography-derived strain parameters were significantly reduced in patients.
- Patients showed 'rigid body rotation' with apical and basal segments moving in the same direction, indicating absent left ventricular twist.
Conclusions:
- Left ventricular function and contractility are severely compromised in noncompaction cardiomyopathy.
- 3D speckle-tracking echocardiography effectively demonstrates reduced strain and the absence of left ventricular twist in these patients.
Introduction:
Noncompaction cardiomyopathy develops due to the absence of myocardial compaction, and is associated with left ventricular dysfunction.
Aim:
The aim of the study was to evaluate comparatively left ventricular dysfunction in patients with noncompaction cardiomyopathy using two-dimensional echocardiography and three-dimensional speckle-tracking echocardiography.
Method:
The present study comprised of 7 patients with noncompaction cardiomyopathy (62.9±8.5 years, 3 males) and 10 age- and gender-matched healthy controls (60.7±7.7 years, 2 males). All patients were examined by two-dimensional echocardiography and three-dimensional speckle-tracking echocardiography for the evaluation of left ventricular function.
Results:
Increased left ventricular end-diastolic and end-systolic volumes and reduced left ventricular ejection fraction were detected in patients with noncompaction cardiomyopathy as compared to those measured in controls. All three-dimensional speckle-tracking echocardiography-derived strain parameters of patients with noncompaction cardiomyopathy were found to be reduced as compared to the values of controls. Three-dimensional speckle-tracking echocardiography-derived rotational parameters showed movements of the apical and basal segments in the same direction suggesting 'rigid body rotation' in all noncompaction cardiomyopathy cases.
Conclusions:
Left ventricular function and contractility are severely reduced in patients with noncompaction cardiomyopathy. Absence of left ventricular twist could be demonstrated in a series of noncompaction cardiomyopathy patients.
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