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Osmotic Avoidance in Caenorhabditis elegans: Synaptic Function of Two Genes, Orthologues of Human NRXN1 and NLGN1, as Candidates for Autism
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Osmotic Avoidance in Caenorhabditis elegans: Synaptic Function of Two Genes, Orthologues of Human NRXN1 and NLGN1, as Candidates for Autism

Published on: December 11, 2009

Interaction between optineurin and the bZIP transcription factor NRL

Chunxia Wang1, Katsuhiro Hosono, Masafumi Ohtsubo

  • 1Department of Ophthalmology, Hamamatsu University School of Medicine, 1-20-1 Handayama, Hamamatsu, 431-3192, Japan; Department of Photomedical Genomics, Basic Medical Photonics Laboratory, Medical Photonics Research Center, Hamamatsu University School of Medicine, 1-20-1 Handayama, Hamamatsu, 431-3192, Japan; Department of Ophthalmology, The Fourth Affiliated Hospital of China Medical University, Shenyang, 110005, China.

Cell Biology International
|August 20, 2013
PubMed
Summary

Optineurin (OPTN) binds to neural retina leucine zipper (NRL), an eye-specific protein. This interaction, localized to the OPTN tail region, occurs in photoreceptor cells, suggesting a novel role in retinal function.

Keywords:
NRLco-immunoprecipitationoptineurinphotoreceptorprotein interactionproximity ligation assay

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