Related Experiment Video
Updated: May 8, 2026

Observation of the Ciliary Movement of Choroid Plexus Epithelial Cells Ex Vivo
Published on: July 13, 2015
Unusually prominent horizontal gaze palsy in a case of Niemann-Pick type C disease
Pritikanta Paul1, Banashree Mondal, Arijit Kumar Mukherjee
1RG Chamaria Medical Research Institute, Institute of Neurosciences, Kolkata, India.
Abstract:
Niemann-Pick Type C disease (NPC) is a rare inherited metabolic disorder characterized by lipid accumulation and systemic manifestations due to multiple organ involvement. Only a few cases of NPC have been reported so far from India. Varying presentations and often lack of access to complex diagnostic tests have leaded to initial misdiagnosis on few occasions. We here report a provisionally diagnosed case of NPC with prominent horizontal gaze palsy along with characteristic vertical gaze palsy and normal findings on microscopic examination of skin biopsy specimen.
Related Concept Videos
Prosopagnosia
Cranial Nerves: Types Part I
Olfactory Nerve (Cranial Nerve I)
The olfactory nerve, or cranial nerve I, is unique as it is purely sensory and dedicated to the sense of smell. This nerve originates in the olfactory epithelium of the...
Photoreceptors and Visual Pathways
Glaucoma: Overview
Lysosomal Hydrolases
