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Updated: May 8, 2026

In Vivo Functional Study of Disease-associated Rare Human Variants Using Drosophila
Published on: August 20, 2019
Ectodermal dysplasia in identical twins
Gurkar Haraswarupa Puttaraju1, Paranjyothi Magadi Visveswariah
1Department of Prosthodontia, Farooqia Dental College, Mysore, Karnataka, India.
Abstract:
Hereditary hypohidrotic ectodermal dysplasia (HED) is typically inherited as an X-linked recessive trait, characterized by deformity of at least two or more of the ectodermal structures - hair, teeth, nails and sweat glands. Two cases of hereditary HED involving identical male twins, is being documented for the rarity of its occurrence with special attention given to genetics, pathophysiology, clinical, intraoral manifestations and to the methods to improve the masticatory function, the facial esthetics and psychology of patients affected by this disease.
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