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Updated: May 8, 2026

Inducing Meningococcal Meningitis Serogroup C in Mice via Intracisternal Delivery

Inducing Meningococcal Meningitis Serogroup C in Mice via Intracisternal Delivery

Published on: November 5, 2019

Meningitis.

Katherine Putz¹, Karen Hayani, Fred Arthur Zar

¹Department of Family Medicine, University of Illinois at Chicago, 1919 West Taylor Street MC 663, Chicago, IL 60612, USA. kasiaputz@gmail.com

|August 21, 2013

Summary

Meningitis involves inflammation of the meninges, often indicated by abnormal white blood cells in cerebrospinal fluid. This review covers acute meningitis, focusing on its epidemiology, diagnosis, and management for primary care.

Keywords:

Acute meningitis Aseptic Blood-brain barrier Cerebrospinal fluid Meningismus Prophylaxis Vaccination

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Induction of Leptomeningeal Cells Modification Via Intracisternal Injection

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Last Updated: May 8, 2026

Inducing Meningococcal Meningitis Serogroup C in Mice via Intracisternal Delivery

Inducing Meningococcal Meningitis Serogroup C in Mice via Intracisternal Delivery

Published on: November 5, 2019

Induction of Leptomeningeal Cells Modification Via Intracisternal Injection

Induction of Leptomeningeal Cells Modification Via Intracisternal Injection

Published on: May 7, 2020

Area of Science:

Neurology
Infectious Diseases
Public Health

Background:

Meningitis is inflammation of the meninges.
It presents with specific clinical signs and cerebrospinal fluid abnormalities.
Acute meningitis develops rapidly over hours to days.

Purpose of the Study:

To review the epidemiology of acute meningitis.
To discuss the pathophysiology, clinical manifestations, and diagnosis.
To outline management strategies and provide key points for primary care practitioners.

Main Methods:

Literature review of epidemiology, pathophysiology, clinical manifestations, diagnosis, and management of acute meningitis.
Separate discussion of aseptic and bacterial meningitis.
Identification of key points for primary care.

Main Results:

Acute meningitis symptoms develop rapidly.
Diagnosis relies on clinical signs and cerebrospinal fluid analysis.
Management strategies differ for aseptic and bacterial meningitis.

Conclusions:

Understanding the epidemiology and pathophysiology is crucial for timely diagnosis.
Prompt diagnosis and appropriate management are essential for patient outcomes.
Primary care practitioners play a vital role in managing acute meningitis.