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Recombinant activated factor VII administration after pulmonary embolectomy: case report
Nedal Omran1, Jan Harrer, Miroslav Brtko
1Department of Cardiac Surgery, Charles University in Prague, Hradec Kralove, Czech Republic. nidal81@gmail.com
The Heart Surgery Forum
|August 21, 2013
Summary
Recombinant activated factor VII (rFVIIa) can manage severe bleeding during pulmonary embolectomy. This case report highlights its rescue use in complex cardiac surgery with coagulopathy.
Area of Science:
- Cardiovascular Surgery
- Hematology
- Anesthesiology
Background:
- Managing coagulopathy during cardiac surgery, especially pulmonary embolectomy, presents significant challenges.
- Recombinant activated factor VII (rFVIIa) is established for postcardiotomy coagulopathy.
- Limited data exists on rFVIIa use in patients with recent thromboembolic events.
Observation:
- A patient undergoing surgical pulmonary embolectomy under cardiopulmonary bypass developed a severe coagulation disorder.
- Standard treatments were insufficient to control the bleeding.
Findings:
- Rescue administration of recombinant activated factor VII (rFVIIa) was successfully employed.
- rFVIIa effectively managed the severe coagulation disorder during the complex procedure.
Implications:
- This case demonstrates the potential utility of rFVIIa as a rescue therapy in challenging bleeding scenarios during cardiac surgery.
- Further research may explore rFVIIa's role in specific coagulopathies associated with thromboembolic events in surgical contexts.
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