Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: May 8, 2026

Sentinel Lymph Node Mapping and Biopsy for Endometrial Cancer at Early Stage with Laparoscopy
05:52

Sentinel Lymph Node Mapping and Biopsy for Endometrial Cancer at Early Stage with Laparoscopy

Published on: August 19, 2021

Selenium levels in neoplastic breast lesions.

O I Alatise1, O O Babalola, G O Omoniyi-Esan

  • 1Department of Surgery, Faculty of Clinical Sciences Obafemi Awolowo University, Ile-Ife, Nigeria. segunalatishe@yahoo.co.uk

The Nigerian Postgraduate Medical Journal
|August 21, 2013
PubMed
Summary

Tissue selenium levels were lower in breast cancer patients compared to fibroadenoma patients. This suggests that low selenium may contribute to breast cancer development.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Knowledge, Attitude and Perception of Medical Students at the University College Hospital, Ibadan towards Female Genital Mutilation.

West African journal of medicine·2025
Same author

Intramural Pregnancy: An Intriguing Diagnosis in a Resource Constraint Practice.

West African journal of medicine·2024
Same author

Pre-and Post-Prostatectomy Detrusor Wall Thickness and the Symptom Profile in Patients with Benign Prostatic Enlargement: A Prospective Review.

West African journal of medicine·2024
Same author

Medical and Dental Students' Perceptions of the Learning Environment during Anatomic Pathology Placement at Obafemi Awolowo University, Ile-Ife, Nigeria.

West African journal of medicine·2022
Same author

Unveiling research training gaps in oncology: Evaluating a research capacity-building effort among Nigerian physicians.

Nigerian journal of clinical practice·2022
Same author

Comparative Immunohistochemical Analysis of p53 and Alpha-SMA in Ameloblastoma, AOT and OKC.

West African journal of medicine·2022

Area of Science:

  • Oncology
  • Biochemistry
  • Nutritional Science

Background:

  • Breast cancer is a significant global health concern.
  • Fibroadenoma is a common benign breast tumor.
  • Selenium is an essential trace element with antioxidant properties.

Purpose of the Study:

  • To investigate the association between tissue selenium levels and breast diseases.
  • To compare selenium concentrations in breast cancer, fibroadenoma, and control tissues.
  • To explore potential links between selenium status and breast cancer risk.

Main Methods:

  • Prospective case-controlled study design.
  • Inclusion of patients with histologically confirmed breast cancer and fibroadenoma.
  • Quantification of selenium levels in breast tissue samples.

More Related Videos

Optimization of a Multiplex RNA-based Expression Assay Using Breast Cancer Archival Material
11:12

Optimization of a Multiplex RNA-based Expression Assay Using Breast Cancer Archival Material

Published on: August 1, 2018

Related Experiment Videos

Last Updated: May 8, 2026

Sentinel Lymph Node Mapping and Biopsy for Endometrial Cancer at Early Stage with Laparoscopy
05:52

Sentinel Lymph Node Mapping and Biopsy for Endometrial Cancer at Early Stage with Laparoscopy

Published on: August 19, 2021

Optimization of a Multiplex RNA-based Expression Assay Using Breast Cancer Archival Material
11:12

Optimization of a Multiplex RNA-based Expression Assay Using Breast Cancer Archival Material

Published on: August 1, 2018

Main Results:

  • Median tissue selenium levels were significantly lower in breast cancer patients (0.0178 mg/g) than in fibroadenoma patients (0.0272 mg/g).
  • Breast cancer was more prevalent in the left breast, while fibroadenoma was more common in the right.
  • Tissue selenium levels were influenced by age, cancer stage, tumor size, reproductive history, and hormone receptor status.

Conclusions:

  • Lower tissue selenium levels are associated with breast cancer.
  • Selenium may play a role in inhibiting carcinogenesis.
  • Reduced tissue selenium concentration could be a contributing factor to breast cancer development.