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Magnetic and Thermal-sensitive Poly(N-isopropylacrylamide)-based Microgels for Magnetically Triggered Controlled Release

Magnetic and Thermal-sensitive Poly(N-isopropylacrylamide)-based Microgels for Magnetically Triggered Controlled Release

Published on: July 4, 2017

Microscale polymer bottles corked with a phase-change material for temperature-controlled release.

Dong Choon Hyun¹, Ping Lu, Sang-Il Choi

¹The Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA 30332 (USA).

Angewandte Chemie (International Ed. in English)

|August 21, 2013

Summary

This summary is machine-generated.

Microscale polystyrene bottles release encapsulated dye instantly when a phase-change material (PCM) melts. This dye release can be controlled by using mixtures of PCMs with varying melting points.

Keywords:

hollow particles phase-change material temperature-controlled release

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Area of Science:

Materials Science
Chemical Engineering
Physical Chemistry

Background:

Microscale containers are essential for controlled substance delivery.
Phase-change materials (PCMs) offer unique thermal properties for triggering events.

Purpose of the Study:

To develop a microscale system for instant dye release using phase-change materials.
To investigate the manipulation of dye release profiles through PCM mixtures.

Main Methods:

Microscale polystyrene (PS) bottles were loaded with dye molecules.
Bottles were sealed using phase-change materials (PCMs).
Temperature-induced melting of PCMs was used to trigger dye release.

Main Results:

Instantaneous release of encapsulated dye was achieved upon PCM melting.
Dye release profiles were successfully modulated by employing binary PCM mixtures with distinct melting points.

Conclusions:

The developed microscale PS bottle system provides a novel method for triggered dye release.
Controlling PCM composition allows for tunable release kinetics, applicable to various micro-delivery systems.