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From data to function: functional modeling of poultry genomics data
1Department of Veterinary Science and Microbiology, University of Arizona, Tucson, AZ 85721, USA. fionamcc@email.arizona.edu
Poultry Science
|August 21, 2013
Summary
Functional genomics in poultry research is advancing with new sequencing technologies. This study highlights available functional modeling resources and strategies for researchers to analyze complex genomic data for agriculture and health applications.
Area of Science:
- Genomics
- Bioinformatics
- Poultry Science
Background:
- Functional genomics aims to understand biological systems for agriculture, human health, and environmental benefits.
- Functional modeling organizes gene and gene product data by function, interactions, and biological pathways.
- Poultry researchers face challenges due to limited functional annotation data, tools, and training.
Purpose of the Study:
- To discuss the impact of new sequencing technologies on poultry research.
- To identify available functional modeling resources for poultry researchers.
- To describe strategies for functional modeling of poultry genomic data.
Main Methods:
- Review of functional modeling approaches, data, and tools.
- Description of methods for functional analysis: Gene Ontology (GO) functional summaries, enrichment analysis, pathway, and network modeling.
- Discussion of emerging cyberinfrastructure for data storage and analysis.
Main Results:
- New sequencing technologies generate vast amounts of poultry genomic data.
- Functional modeling resources and strategies are becoming more accessible.
- Improved gene identification, nomenclature, expression data, and gene product function are crucial.
Conclusions:
- Advancements in annotation and cyberinfrastructure support poultry functional genomics.
- These developments will enable researchers to better interpret functional genomics datasets.
- This work provides a starting point for poultry researchers utilizing functional modeling tools.
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