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Related Concept Videos

Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...

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Related Experiment Video

Updated: May 8, 2026

Sentinel Lymph Node Mapping and Biopsy for Endometrial Cancer at Early Stage with Laparoscopy
05:52

Sentinel Lymph Node Mapping and Biopsy for Endometrial Cancer at Early Stage with Laparoscopy

Published on: August 19, 2021

Sentinel lymph node biopsy for cutaneous melanoma: a 6 years study.

Jaime Lima Sánchez1, M Sánchez Medina, O García Duque

  • 1Department of Plastic, Reconstructive and Aesthetic Surgery, Universitary Hospital of Gran Canaria, Dr. Negrín, Las Palmas de Gran Canaria, Spain.

Indian Journal of Plastic Surgery : Official Publication of the Association of Plastic Surgeons of India
|August 21, 2013
PubMed
Summary

Sentinel lymph node biopsy (SLNB) is crucial for cutaneous melanoma staging. Positive SLNB results and ulcerated melanoma significantly increase recurrence and mortality risk, highlighting the importance of accurate staging.

Keywords:
Melanomasentinel node biopsysentinel node dissection

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Area of Science:

  • Oncology
  • Dermatology
  • Surgical Pathology

Background:

  • Cutaneous melanoma management relies on accurate staging.
  • Sentinel lymph node biopsy (SLNB) is a key staging procedure.
  • Evaluating SLNB outcomes is vital for patient prognosis.

Purpose of the Study:

  • To assess the efficacy and outcomes of SLNB in cutaneous melanoma patients.
  • To identify prognostic factors influencing survival and recurrence.
  • To correlate SLNB status with clinicopathological features.

Main Methods:

  • Retrospective analysis of 128 cutaneous melanoma patients undergoing SLNB.
  • Univariate and multivariate analyses to determine predictors of mortality and SLNB status.
  • Kaplan-Meier survival analysis to evaluate patient outcomes.

Main Results:

  • A 27.3% SLNB positivity rate was observed.
  • Higher Breslow thickness and ulceration were associated with positive SLNB and recurrence.
  • SLNB-positive patients had a significantly higher recurrence rate (40%) and mortality risk.

Conclusions:

  • Sentinel lymph node status is a significant independent prognostic factor in cutaneous melanoma.
  • Ulcerated melanomas have a higher risk of recurrence and mortality.
  • SLNB is essential for risk stratification and guiding treatment decisions.