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Contact Hypersensitivity as a Murine Model of Allergic Contact Dermatitis

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Published on: September 26, 2022

Allergic contact dermatitis to superglue.

L Sornakumar¹, C Shanmugasekar, Reena Rai

¹Department of Dermatology, PSGIMSR, Coimbatore, Tamil Nadu, India.

International Journal of Trichology

|August 21, 2013

Summary

This summary is machine-generated.

Allergic reactions to wig adhesives can cause scalp inflammation. A rare case identified 2-hydroxy ethyl methacrylate in superglue as the cause of a patient's forehead rash.

Keywords:

Patch test superglue wig

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Area of Science:

Dermatology
Contact Allergy
Allergen Identification

Background:

Wigs are frequently used for cosmetic purposes, particularly to conceal alopecia.
Scalp conditions can arise from the use of wigs and associated adhesives.
Identifying the specific allergen is crucial for effective patient management.

Observation:

A 28-year-old male presented with pruritic, erythematous, and oozing lesions on his forehead.
The lesions were located at the site where a wig was affixed to the scalp.
The patient's symptoms indicated a potential contact dermatitis.

Findings:

Patch testing was performed using the Indian Standard Series and Dental Series.
Positive reactivity was observed for 2-hydroxy ethyl methacrylate.
This methacrylate is a known component of cyanoacrylate-based adhesives, commonly referred to as superglue.

Implications:

This case highlights 2-hydroxy ethyl methacrylate as a potential allergen in wig adhesives.
Accurate diagnosis through patch testing is essential for managing contact dermatitis related to cosmetic devices.
Clinicians should consider adhesive components when evaluating scalp reactions in wig users.