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Updated: May 8, 2026

A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair
Published on: October 16, 2021
Moderate ischemic mitral regurgitation: Is there a case for early intervention?
Hani K Najm1, Ahmed A Arifi, Ahmed S Omran
1Section of Cardiac Surgery, Department of Cardiac Sciences, King Abdulaziz Cardiac Center, National Guard Health Affairs, Saudi Arabia.
Ischemic mitral regurgitation (IMR) negatively impacts survival after heart attack. This review examines evidence for surgically correcting IMR during coronary artery bypass surgery, especially for moderate cases.
Area of Science:
- Cardiology
- Cardiac Surgery
- Heart Valve Disease
Background:
- Ischemic mitral regurgitation (IMR) arises from left ventricular remodeling post-myocardial infarction.
- IMR significantly increases cardiovascular mortality and morbidity.
- It is a recognized negative prognostic factor for long-term survival in patients undergoing coronary artery bypass grafting (CABG).
Purpose of the Study:
- To highlight the detrimental long-term survival impact of IMR.
- To review the evidence supporting surgical correction of IMR during CABG.
- To aid decision-making in moderate IMR cases during revascularization.
Main Methods:
- Literature review of studies on ischemic mitral regurgitation.
- Analysis of prognostic data related to IMR and survival.
- Evaluation of surgical outcomes for IMR correction during CABG.
Main Results:
- Severe IMR necessitates correction during CABG.
- Decision-making for moderate IMR is complex.
- Evidence suggests potential survival benefits from surgical correction.
Conclusions:
- IMR poses a significant threat to long-term survival.
- Surgical correction of IMR during CABG warrants careful consideration.
- Further evidence supports intervention in select moderate IMR cases.
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