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Updated: May 8, 2026

Echocardiographic Approaches and Protocols for Comprehensive Phenotypic Characterization of Valvular Heart Disease in Mice
Published on: February 14, 2017
Echocardiography of the mitral valve
A S Omran1, A A Arifi, A A Mohamed
1Department of Cardiac Sciences, King Abdul Aziz Cardiac Center, National Guard Health Affairs, Saudi Arabia.
Insights
This review covers the structural and hemodynamic evaluation of the normal mitral valve, a key focus in echocardiography for diagnosing valvular heart disease.
Area of Science:
- Cardiology
- Medical Imaging
- Cardiac Anatomy
Background:
- Mitral valve disease is a prevalent global condition, second only to aortic valve disease.
- The mitral valve has been a significant focus for early echocardiography pioneers.
- Echocardiography's initial applications included diagnosing valvular heart conditions like mitral stenosis.
Purpose of the Study:
- To provide a comprehensive overview of the normal mitral valve.
- To detail the structural assessment of the mitral valve using echocardiography.
- To explain the hemodynamic evaluation of a healthy mitral valve.
Main Methods:
- Review of historical and current echocardiographic techniques.
- Analysis of anatomical landmarks for mitral valve assessment.
- Description of hemodynamic principles relevant to mitral valve function.
Main Results:
- Detailed description of normal mitral valve anatomy.
- Explanation of echocardiographic parameters for structural evaluation.
- Outline of hemodynamic assessments for normal mitral valve function.
Conclusions:
- Understanding the normal mitral valve is crucial for diagnosing pathology.
- Echocardiography remains a cornerstone in evaluating mitral valve structure and function.
- This review serves as a foundational guide for mitral valve assessment.
Abstract:
Mitral valve disease is the second most common valvular heart disease after the aortic valve worldwide. Mitral valve has historically been a structure of interest by pioneers in echocardiography. One of the earliest applications of echocardiography was in the diagnosis of valvular heart disease, particularly mitral stenosis. In this review we wish to take the reader through the structural and hemodynamic evaluation of the normal mitral valve.
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