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Updated: May 8, 2026

A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair
Published on: October 16, 2021
Tenecteplase in prosthetic mitral valve thrombosis
Masood Ayyub Ghori1, Sherif Bakir, Samer Ellahham
1Cardiac Science Department, Sheikh Khalifa Medical City, Abu Dhabi, United Arab Emirates.
Abstract:
In the few reported cases of prosthetic mitral valve thrombosis, where surgical intervention was considered as high risk, fibrinolytic therapy had proved life saving. The authors present clinical, laboratory, and imaging data from such a patient, with prosthetic mitral valve thrombosis and its successful management with tenecteplase. The use of tenecteplase as a viable fibrinolytic agent for the first time was justified, due to the lack of immunogenicity concerns compared to streptokinase.
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