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Related Concept Videos

Site-Targeted Drug Delivery Systems: Polymeric Carriers01:24

Site-Targeted Drug Delivery Systems: Polymeric Carriers

Polymeric carriers enhance targeted drug delivery by increasing efficacy while minimizing off-target effects. These carriers comprise a biodegradable polymeric backbone integrated with functional elements that enable targeting, improve physicochemical properties, and regulate drug release.Targeting MechanismsThe targeting ability of polymeric carriers is mediated by a homing device, which is a molecular recognition component designed to selectively bind to specific tissues or cells. Monoclonal...
Modified-Release Drug Delivery Systems: Site-Targeted01:24

Modified-Release Drug Delivery Systems: Site-Targeted

Site-targeted drug delivery systems enhance therapeutic efficacy while minimizing systemic toxicity and treatment costs. Unlike conventional methods, these systems ensure precise drug delivery, improving bioavailability and reducing side effects. Targeted drug delivery is classified into three levels. First-order targeting directs drugs to the capillary beds of specific organs or tissues. Second-order targets specific cell types, such as tumor cells, using receptor-mediated interactions.
Drug Delivery: Overview01:16

Drug Delivery: Overview

The selection of a drug's delivery route depends upon its physicochemical properties, including lipid or water solubility and ionization, as well as the therapeutic requirement, such as immediate or sustained effect. These routes can be divided into three primary categories: enteral, parenteral, and topical.
Enteral delivery involves administering drugs directly through swallowing, sublingual placement, or buccal application. Orally administered drugs predominantly navigate the gastrointestinal...
Drug Delivery Systems: Different Types01:27

Drug Delivery Systems: Different Types

Conventional oral drug products, termed immediate-release (IR) formulations, are engineered to promptly release their active pharmaceutical ingredient (API) upon ingestion, typically in tablets or capsules. This rapid release often results in swift drug absorption and consequent pharmacodynamic effects, although the timing and intensity can vary depending on the drug's properties. Prodrugs within these formulations require metabolic conversion to activate their pharmacodynamic effects,...
Oral Drug Delivery Systems: Introduction01:23

Oral Drug Delivery Systems: Introduction

Oral drug delivery is the most common route of administration due to its convenience, cost-effectiveness, and high patient compliance. It enables precise formulation to ensure proper drug dosage and bioavailability. The development of oral dosage forms considers drug properties such as solubility, stability, and absorption to optimize therapeutic efficacy.Tablets, capsules, liquids, and chewable formulations enhance drug stability, mask undesirable tastes, and improve patient experience.
Modified-Release Drug Delivery Systems: Overview01:19

Modified-Release Drug Delivery Systems: Overview

Modified-release dosage forms are designed to address the limitations of drugs with short biological half-lives. These forms maintain stable therapeutic drug concentrations over extended periods, reducing the need for frequent dosing. A consistent drug level helps minimize peak-trough fluctuations, which can reduce adverse effects, lower the risk of drug resistance, and improve overall treatment effectiveness.One common type of modified-release form is the extended-release (ER) formulation. ER...

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Related Experiment Video

Updated: May 8, 2026

Manufacture and Drug Delivery Applications of Silk Nanoparticles
09:03

Manufacture and Drug Delivery Applications of Silk Nanoparticles

Published on: October 8, 2016

Nanoparticles: Emerging carriers for drug delivery.

Sagar R Mudshinge1, Amol B Deore, Sachin Patil

  • 1NDMVP's College of Pharmacy, Nashik 422005, Maharashtra, India.

Saudi Pharmaceutical Journal : SPJ : the Official Publication of the Saudi Pharmaceutical Society
|August 21, 2013
PubMed
Summary

Nanoparticles offer precise control over cellular components for improved health. Developing controllable synthetic nanostructures is key to advancing nanotherapeutics and understanding diseases like cancer.

Keywords:
BiomacromolecularDiagnosticsNanoparticlesNanoscaleNanostructuresSupramolecular

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Facile Preparation of Internally Self-assembled Lipid Particles Stabilized by Carbon Nanotubes
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Facile Preparation of Internally Self-assembled Lipid Particles Stabilized by Carbon Nanotubes

Published on: February 19, 2016

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Last Updated: May 8, 2026

Manufacture and Drug Delivery Applications of Silk Nanoparticles
09:03

Manufacture and Drug Delivery Applications of Silk Nanoparticles

Published on: October 8, 2016

Facile Preparation of Internally Self-assembled Lipid Particles Stabilized by Carbon Nanotubes
09:47

Facile Preparation of Internally Self-assembled Lipid Particles Stabilized by Carbon Nanotubes

Published on: February 19, 2016

Area of Science:

  • Biotechnology
  • Nanomedicine
  • Molecular Biology

Background:

  • Biomacromolecular constructs and supramolecular assemblies are vital for cellular functions and human health.
  • Nanoscale entities like drugs, proteins, DNA/RNA, and viruses are involved in critical biological events.
  • Understanding these nanoscale interactions is crucial for addressing human diseases and longevity.

Purpose of the Study:

  • To highlight the importance of nanoparticles in controlling nanoscale biological entities.
  • To emphasize the potential of nanotherapeutics and diagnostics for understanding human health and disease.
  • To underscore the need for a versatile technology platform for synthetic nanostructures.

Main Methods:

  • The study focuses on the conceptual framework and potential applications of nanoparticles.
  • It discusses the manipulation of biomacromolecular constructs and supramolecular assemblies.
  • The text emphasizes the development of controllable synthetic nanostructures.

Main Results:

  • Nanoparticles enable precise control over nanoscale biological components.
  • Nanotherapeutics and diagnostics promise deeper insights into human longevity and diseases.
  • A flexible technology platform for synthetic nanostructures is essential.

Conclusions:

  • Nanoparticles are critical tools for manipulating cellular machinery to enhance human health.
  • Advancements in nanomedicine will deepen our understanding of complex diseases and aging.
  • Developing controllable, tunable synthetic nanostructures is a foundational step for future innovations.