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Related Concept Videos

Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
Acne Infection01:27

Acne Infection

Acne is a multifactorial skin condition primarily affecting adolescents and young adults, with a global prevalence estimated to exceed 75% in this demographic. The condition is characterized by the formation of comedones (blackheads and whiteheads), papules, pustules, nodules, and, in severe cases, cysts, particularly in areas rich in sebaceous glands such as the face, neck, chest, and back. The pathogenesis involves increased sebum production, follicular hyperkeratinization, colonization by...
Anthelminthic Agents01:15

Anthelminthic Agents

Anthelmintic drugs differ significantly from antiparasitic therapies targeting protozoa, primarily due to differences in parasite biology. Whereas most protozoal treatments act on proliferating cells, anthelmintics are typically directed against mature, nonproliferative helminths. The therapeutic approach considers the helminth's reliance on neuromuscular coordination, glucose metabolism, and microtubular integrity for survival, reproduction, and localization within the host. Most anthelmintics...
Blinding01:11

Blinding

Blinding is a commonly used method of not telling participants which treatment a subject is receiving. Blinding is a critical part of a randomized control trial or RCT. It reduces the bias that affects the results. In an RCT, blinding is used in the form of a placebo. A placebo effect occurs when untreated subjects falsely believe they have received the treatment and report improved symptoms. A placebo or a dummy treatment is administered to subjects to negate the bias caused by such an effect.

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Related Experiment Video

Updated: May 8, 2026

Surgical Correction for Pediatric Epiblepharon and Trichiasis
03:59

Surgical Correction for Pediatric Epiblepharon and Trichiasis

Published on: July 8, 2025

Eradicating blinding trachoma: What is working?

Imtiaz A Chaudhry1

  • 1Oculoplastic and Orbit Division, King Khaled Eye Specialist Hospital, P.O. Box 7191, Riyadh 11462, Saudi Arabia.

Saudi Journal of Ophthalmology : Official Journal of the Saudi Ophthalmological Society
|August 21, 2013
PubMed
Summary

Trachoma, a leading cause of preventable blindness, is declining due to the SAFE strategy. However, long-term scarring complications still cause vision loss, particularly in females, requiring ongoing management.

Keywords:
Adnexal complicationsChlamydia trachomatisEvaluationTrachomaTreatmentVisual loss

Related Experiment Videos

Last Updated: May 8, 2026

Surgical Correction for Pediatric Epiblepharon and Trichiasis
03:59

Surgical Correction for Pediatric Epiblepharon and Trichiasis

Published on: July 8, 2025

Area of Science:

  • Ophthalmology
  • Infectious Diseases
  • Public Health

Background:

  • Trachoma is a major cause of preventable corneal blindness globally, primarily affecting children through ocular Chlamydia trachomatis infections.
  • Untreated follicular conjunctivitis can lead to scarring of the conjunctiva and eyelids, resulting in corneal scarring and vision loss.

Purpose of the Study:

  • To review the impact of the SAFE strategy on trachoma prevalence and discuss long-term complications.
  • To highlight the persistent challenges of adnexal and lacrimal complications leading to visual impairment despite trachoma control efforts.

Main Methods:

  • Review of existing literature on trachoma prevalence, the SAFE strategy, and its long-term sequelae.
  • Analysis of clinical manifestations and complications associated with trachomatous scarring.

Main Results:

  • Significant reduction in active trachoma prevalence attributed to the WHO's GET 2020 program and the SAFE strategy.
  • Persistent adnexal complications (trichiasis, entropion, eyelid retraction) and lacrimal issues (duct obstruction, dacryocystitis) in individuals with prior infection.
  • Increased risk of microbial keratitis and corneal scarring from trichiasis/entropion, with females disproportionately affected.

Conclusions:

  • The SAFE strategy is effective in reducing trachoma prevalence and is progressing towards the GET 2020 goal.
  • Ongoing vigilance and management of trachomatous scarring complications are crucial for preventing irreversible vision loss.
  • Addressing gender-specific vulnerabilities is important for comprehensive trachoma elimination efforts.