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Cow's milk allergy in multiple sclerosis patients

Fereshteh Ashtari1, Fatemeh Jamshidi, Raheleh Shokouhi Shoormasti

  • 1Department of Neurology, Isfahan Neuroscience Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.

Journal of Research in Medical Sciences : the Official Journal of Isfahan University of Medical Sciences
|August 21, 2013
PubMed
Abstract

Insights

This study found no significant difference in cow's milk allergy (CMA) between multiple sclerosis (MS) patients and healthy individuals. Further research is needed to understand environmental factors in MS development.

Area of Science:

  • Neurology
  • Immunology
  • Environmental Health

Background:

  • Environmental factors like nutrition and allergens may influence multiple sclerosis (MS) development.
  • Cow's milk allergy (CMA) is a potential environmental factor under investigation.
  • This study aimed to compare CMA prevalence in MS patients versus healthy controls.

Purpose of the Study:

  • To evaluate the frequency of cow's milk allergy (CMA) in patients with multiple sclerosis (MS).
  • To compare the prevalence of CMA in MS patients against a healthy control group.

Main Methods:

  • A cohort of 48 MS patients was compared with 48 healthy subjects.
  • Cow's milk specific immunoglobulin E (IgE) levels were measured using Immuno CAP.
  • Chi-square test was used to compare sex and CMA frequency between groups.

Main Results:

  • No cow's milk specific IgE was detected in the serum of either MS patients or healthy controls.
  • The study included 96 subjects (22% male, 78% female) with a mean age of 30.8 ± 6.6 years.
  • No statistically significant difference in CMA was observed between the MS and control groups (P value = 0.83).

Conclusions:

  • There is no discernible difference in cow's milk allergy between individuals with multiple sclerosis and healthy subjects.
  • The findings suggest CMA is not a differentiating factor between MS patients and controls in this cohort.
Keywords:
Allergycow's milkmultiple sclerosis

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