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Two new ursolic acid saponins from Morina nepalensis var. alba Hand-Mazz
Zhi-feng Zhang1, Lu-yang Lu, Pei Luo
1a Ethnic Pharmaceutical Institute, Southwest University for Nationalities , Chengdu , 610041 , Sichuan Province P.R. China.
Abstract:
A saponin-enriched fraction was prepared from the EtOH extract of the whole plant of Morina nepalensis var. alba Hand-Mazz. It showed α-glucosidase inhibitory activity, from which two new triterpene saponins (1 and 2), along with one known saponin (3), were isolated. The structures of the new saponins were identified by spectroscopic analysis, including extensive 1D and 2D NMR techniques and hydrolysis followed by chromatographic analysis. The three saponins were assayed for α-glucosidase inhibitory activities.