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Related Concept Videos

Colonisation of Pathogens01:25

Colonisation of Pathogens

Pathogen colonization of host tissues is a critical step in the development of infectious diseases. Various pathogenic microorganisms, including bacteria, fungi, viruses, and protozoa, have evolved complex strategies to attach to, invade, and persist within host environments. These mechanisms enable pathogens to establish infections, evade immune responses, and resist antimicrobial treatments.Attachment to Host CellsIn bacteria, colonization typically begins with adherence to host epithelial...
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Fungal Phylum Microsporidia

Microsporidia are a group of obligate intracellular fungi that were initially classified as protists but were later reclassified based on phylogenetic, molecular, and structural evidence linking them to the Chytridiomycota. These unicellular, non-motile organisms are highly specialized parasites that infect a wide range of animal hosts, including humans. They have evolved extensive genomic and metabolic reductions, making them highly dependent on their hosts for survival.Morphology and Genomic...
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Fungal Phylum Ascomycota

Phylum Ascomycota, a major division within the subkingdom Dikarya, comprises a diverse range of fungal species, including both unicellular yeasts and filamentous molds such as Aspergillus and Penicillium. These fungi thrive in a variety of habitats, from aquatic ecosystems to terrestrial environments, playing crucial ecological and economic roles.Morphology and ReproductionThe defining characteristic of Ascomycetes, commonly referred to as sac fungi, is the ascus—a sac-like structure that...
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Fungal Group Zygomycota

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Related Experiment Video

Updated: May 8, 2026

Visualization of Candida albicans in the Murine Gastrointestinal Tract Using Fluorescent In Situ Hybridization
10:08

Visualization of Candida albicans in the Murine Gastrointestinal Tract Using Fluorescent In Situ Hybridization

Published on: November 5, 2019

Candida albicans, plasticity and pathogenesis.

Daniel Poulain1

  • 1Unité 995 Inserm-Université Lille2, Faculté de Médecine & Centre Hospitalier Universitaire , Lille , France.

Critical Reviews in Microbiology
|August 22, 2013
PubMed
Summary
This summary is machine-generated.

Candida albicans causes various infections, from common yeast infections to life-threatening hospital-acquired diseases. Early diagnosis and understanding its pathogenic adaptation are crucial for effective control.

Keywords:
Candida cell wallcandidosisdiagnosisgenetic factorsimmunity

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An Ex vivo Assay to Study Candida albicans Hyphal Morphogenesis in the Gastrointestinal Tract
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Last Updated: May 8, 2026

Visualization of Candida albicans in the Murine Gastrointestinal Tract Using Fluorescent In Situ Hybridization
10:08

Visualization of Candida albicans in the Murine Gastrointestinal Tract Using Fluorescent In Situ Hybridization

Published on: November 5, 2019

An Ex vivo Assay to Study Candida albicans Hyphal Morphogenesis in the Gastrointestinal Tract
07:42

An Ex vivo Assay to Study Candida albicans Hyphal Morphogenesis in the Gastrointestinal Tract

Published on: July 1, 2020

Area of Science:

  • Medical Mycology
  • Infectious Diseases
  • Molecular Pathogenesis

Background:

  • Candida albicans is a significant public health concern, causing a wide range of infections.
  • These infections span from common vaginal candidiasis to severe, life-threatening invasive candidiasis in hospitalized patients.
  • The yeast's role in chronic inflammatory bowel diseases is also under investigation.

Purpose of the Study:

  • To review modern concepts of Candida pathogenesis.
  • To highlight the specific adaptive traits of Candida albicans that contribute to its pathogenicity.
  • To emphasize the need for improved diagnostic strategies and interdisciplinary collaboration.

Main Methods:

  • This review synthesizes current research on Candida albicans pathogenesis.
  • It includes examples illustrating the yeast's pathogenic adaptation mechanisms.
  • The review draws upon clinical observations and molecular biology findings.

Main Results:

  • Candida albicans exhibits remarkable adaptability, enabling it to cause diverse infections.
  • Despite advances, controlling nosocomial Candida infections remains challenging due to diagnostic difficulties.
  • Understanding the molecular and genetic factors influencing host-pathogen interactions is key.

Conclusions:

  • Early identification of the transition from commensal to pathogen is critical for patient outcomes.
  • Enhanced dialogue between biologists and clinicians is essential for timely diagnosis and treatment.
  • Further research into Candida pathogenesis and host adaptation is needed to combat its growing threat.