Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Enteral Nutrition II: Nasointestinal and Gastrostomy Feeding01:15

Enteral Nutrition II: Nasointestinal and Gastrostomy Feeding

Enteral nutrition encompasses various methods of delivering nutrition directly to the gastrointestinal (GI) tract, bypassing traditional oral intake. It is particularly beneficial for patients who cannot eat by mouth but have a functioning digestive system. Key methods include nasointestinal feeding, gastrostomy, and jejunostomy, each suited to different clinical scenarios based on the patient's needs and condition.
Nasointestinal Feeding
Nasointestinal feeding involves placing a tube through...
Enteral Nutrition I: Orogastric and Nasogastric Feeding01:26

Enteral Nutrition I: Orogastric and Nasogastric Feeding

Enteral nutrition delivers nutrients directly to the stomach or small intestine through a tube. This method is appropriate for patients who cannot eat but still have a functioning digestive system. It is also beneficial for individuals with swallowing difficulties, anorexia, malabsorption, or those who have undergone gastrointestinal (GI) surgery.
Orogastric (OG) and nasogastric (NG) feeding are two standard methods used for enteral nutrition. Enteral nutrition is often preferred over...
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy01:30

Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy

Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the colonic...
Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption01:23

Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption

Understanding the physiological differences in the pediatric population is crucial for effective pharmacotherapy. Neonates, infants, and children exhibit significant variations in gastric pH, gastric emptying time, intestinal transit time, and biliary function. These variations profoundly affect oral drug absorption, necessitating a nuanced approach to pediatric dosing.Neonates present with a unique physiological profile, having a gastric pH greater than 4 and faster and more irregular gastric...
Inborn Errors of Metabolism01:20

Inborn Errors of Metabolism

Phenylketonuria (PKU) is a protein metabolism disorder characterized by high blood levels of the amino acid phenylalanine. This results from a mutation in the gene responsible for phenylalanine hydroxylase, an enzyme that converts phenylalanine into tyrosine. When this enzyme is deficient, phenylalanine builds up in the blood, leading to symptoms such as vomiting, rashes, seizures, growth deficiency, and severe mental retardation. An early diagnosis and a diet restricting phenylalanine intake...
Development of Human Microbiota01:30

Development of Human Microbiota

The human microbiota begins developing at birth and undergoes continual change as we age. Infancy marks a critical period of microbial sensitivity, offering a “window of opportunity” during which beneficial microbes help mature the immune system. By age three, children typically develop a more stable and diverse microbial community. Newborns acquire microbes from their immediate environment; vaginal delivery favors maternal vaginal microbes, while cesarean births favor microbes from the skin...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Correction to: Real-world use of Serial Clinical Observation in culture-proven early-onset sepsis: timing of recognition, treatment and retrospective comparison with the Neonatal Sepsis Calculator.

European journal of pediatrics·2026
Same author

Real-world use of Serial Clinical Observation in culture-proven early-onset sepsis: timing of recognition, treatment and retrospective comparison with the Neonatal Sepsis Calculator.

European journal of pediatrics·2026
Same author

Ketogenic Strategies in Neonatal Hypoxic-Ischemic Encephalopathy-The Road to Opening Up: A Scoping Review.

Neurology international·2026
Same author

Antimicrobial Therapies for Early-Onset Group B Streptococcal Sepsis: Insights from an Italian Multicenter Study.

Antibiotics (Basel, Switzerland)·2025
Same author

Lumbar Puncture and Meningitis in Infants with Proven Early- or Late-Onset Sepsis: An Italian Prospective Multicenter Observational Study.

Microorganisms·2023
Same author

Timing of Symptoms of Early-Onset Sepsis after Intrapartum Antibiotic Prophylaxis: Can It Inform the Neonatal Management?

Pathogens (Basel, Switzerland)·2023

Related Experiment Video

Updated: May 8, 2026

Effect of Hyaluronic Acid 35 kDa on an In Vitro Model of Preterm Small Intestinal Injury and Healing Using Enteroid-Derived Monolayers
09:36

Effect of Hyaluronic Acid 35 kDa on an In Vitro Model of Preterm Small Intestinal Injury and Healing Using Enteroid-Derived Monolayers

Published on: July 28, 2022

Feeding intolerance in the preterm infant.

Silvia Fanaro1

  • 1Neonatal Intensive Care Unit, Paediatric Section, University of Ferrara, Italy.

Early Human Development
|August 22, 2013
PubMed
Summary

Feeding intolerance (FI) in preterm infants, often due to immature gut function, can mimic serious conditions. This review covers its aspects, prevention, and treatment strategies.

Area of Science:

  • Neonatalogy
  • Gastroenterology
  • Pediatric Nutrition

Background:

  • Feeding intolerance (FI) is common in very preterm infants, characterized by difficulty digesting enteral feedings.
  • FI symptoms like increased gastric residuals, abdominal distension, and emesis can overlap with necrotizing enterocolitis, complicating management.
  • Suboptimal nutrition and delayed feeding can result from inconsistent FI interpretation.

Purpose of the Study:

  • To review the pathophysiology, clinical presentation, and management of feeding intolerance in very preterm infants.
  • To summarize evidence-based prevention and treatment strategies for feeding intolerance.
  • To address practical considerations in managing feeding intolerance in this vulnerable population.

Main Methods:

  • Literature review of studies on feeding intolerance in very preterm infants.
Keywords:
Enteral feedingFeeding intoleranceGastric residualPreterm

More Related Videos

Non-Nutritive Suck Parameters Measurements Using a Custom Pressure Transducer System
06:19

Non-Nutritive Suck Parameters Measurements Using a Custom Pressure Transducer System

Published on: April 19, 2024

Breast Milk Enhances Growth of Enteroids: An Ex Vivo Model of Cell Proliferation
09:02

Breast Milk Enhances Growth of Enteroids: An Ex Vivo Model of Cell Proliferation

Published on: February 15, 2018

Related Experiment Videos

Last Updated: May 8, 2026

Effect of Hyaluronic Acid 35 kDa on an In Vitro Model of Preterm Small Intestinal Injury and Healing Using Enteroid-Derived Monolayers
09:36

Effect of Hyaluronic Acid 35 kDa on an In Vitro Model of Preterm Small Intestinal Injury and Healing Using Enteroid-Derived Monolayers

Published on: July 28, 2022

Non-Nutritive Suck Parameters Measurements Using a Custom Pressure Transducer System
06:19

Non-Nutritive Suck Parameters Measurements Using a Custom Pressure Transducer System

Published on: April 19, 2024

Breast Milk Enhances Growth of Enteroids: An Ex Vivo Model of Cell Proliferation
09:02

Breast Milk Enhances Growth of Enteroids: An Ex Vivo Model of Cell Proliferation

Published on: February 15, 2018

  • Synthesis of information on pathophysiology, clinical signs, and diagnostic challenges.
  • Analysis of prevention and treatment strategies from clinical trials and systematic reviews.

    • Main Results:

    • Feeding intolerance is frequently observed in very preterm infants, often linked to gastrointestinal immaturity.
    • Differentiating FI from necrotizing enterocolitis is challenging due to overlapping symptoms.
    • Limited large-scale, validated strategies exist for FI prevention and treatment.

    Conclusions:

    • Consistent interpretation of FI signs is crucial for optimal nutritional management in preterm infants.
    • Further research and validated interventions are needed to effectively prevent and treat feeding intolerance.
    • Addressing practical issues in FI management is essential for improving outcomes.