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Updated: May 8, 2026
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Modified MicroSecure Vitrification: A Safe, Simple and Highly Effective Cryopreservation Procedure for Human Blastocysts
Published on: March 2, 2017
[Embryo vitrification: French clinical practice analysis for BLEFCO]
L Hesters1, N Achour-Frydman, J Mandelbaum
1Unité de biologie de la reproduction, service d'histologie embryologie cytogénétique, AP-HP, CHU Antoine-Béclère, 157, rue Porte-de-Trivaux, 92140 Clamart, France. laetitia.hesters@abc.aphp.fr
Gynecologie, Obstetrique & Fertilite
|August 22, 2013
Summary
Vitrification, an ultrarapid cryopreservation method, shows improved embryo survival and clinical pregnancy rates compared to slow freezing in assisted reproductive technology (ART). This suggests vitrification enhances ART outcomes and cumulative pregnancy rates per oocyte retrieval.
Area of Science:
- Reproductive biology
- Assisted reproductive technology (ART)
Context:
- Vitrification is a newer ultrarapid cryopreservation method for human embryos.
- Vitrification is now authorized in France for embryo cryopreservation.
- Slow freezing has been the standard ART cryopreservation method for two decades.
Purpose:
- To evaluate the current state of vitrification in French clinical practice.
- To compare vitrification outcomes with traditional slow freezing methods.
- To assess the impact of vitrification on assisted reproductive technology (ART) success rates.
Summary:
- A descriptive study surveyed 60 out of 105 French reproductive biology centers on vitrification practices.
- Data indicated higher embryo survival and clinical pregnancy rates with vitrification versus slow freezing.
- Preliminary findings suggest vitrification improves cumulative pregnancy rates per oocyte retrieval.
Impact:
- Vitrification may enhance overall assisted reproductive technology (ART) outcomes.
- This technology has the potential to increase clinical pregnancy rates.
- The findings support the broader adoption of vitrification in ART.
