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The SAMHD1 knockout mouse model: in vivo veritas?

Ferdinand Roesch1, Olivier Schwartz

  • 1Institut Pasteur, Department of Virology; CNRS; and Université Paris Diderot, Sorbonne Paris Cité, Paris, France.

The EMBO Journal
|August 22, 2013
PubMed
Summary

No abstract available in PubMed .

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In-vitro Mutagenesis01:16

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To learn more about the function of a gene, researchers can observe what happens when the gene is inactivated or “knocked out,” by creating genetically engineered knockout animals. Knockout mice have been particularly useful as models for human diseases such as cancer, Parkinson’s disease, and diabetes.

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