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Chronic pancreatitis as presentation of Crohn's disease in a child
Insights
Idiopathic chronic pancreatitis can be an early sign of Crohn's Disease (CD) in children. Investigating inflammatory bowel disease is crucial when other causes of pancreatitis are ruled out.
Area of Science:
- Gastroenterology
- Pediatric Gastroenterology
- Hepatology
Background:
- Pancreatic diseases can precede inflammatory bowel disease (IBD) diagnoses in both pediatric and adult populations.
- Idiopathic chronic pancreatitis occasionally co-exists with IBD, predominantly in pediatric cases.
Observation:
- A case report details a patient who developed chronic pancreatitis features before a Crohn's Disease (CD) diagnosis.
- The patient experienced pancreatitis symptoms, followed by bloody diarrhea, mucus stools, and inflammatory markers ten months later.
Findings:
- Colonoscopy revealed diffuse colitis, and gastroscopy showed duodenal inflammation.
- Histological examination confirmed CD involving the colon and duodenum.
Implications:
- Idiopathic chronic pancreatitis may represent an unusual initial presentation of CD in children.
- Non-invasive screening for IBD is recommended in pediatric cases of idiopathic chronic pancreatitis.
- Early diagnosis of IBD can potentially slow the progression of pancreatic disease.
Abstract:
It is reported that a pancreatic disease may precede the diagnosis of inflammatory bowel disease (IBD) both in children and in adults. Idiopathic chronic pancreatitis, however, occasionally co-exists with the IBD, mainly at pediatric age. We report a case of a patient who progressively developed the features of a chronic pancreatitis, before the diagnosis of Crohn's Disease (CD). Ten months after the onset of the first episode of pancreatitis the patient developed bloody diarrhea, mucus stools and biochemical findings of inflammation. The colonoscopy revealed a diffuse colitis without involvement of the last loop and the gastroscopy showed inflammation of the iuxta-papillary area. The histological findings confirmed the diagnosis of CD that involved the colon and the duodenum. In conclusion, in children the idiopathic chronic pancreatitis may be an unusual presentation of CD. Thus, if other known cause of chronic pancreatitis are not found, a not invasive work up to exclude the IBD should be warranted. An early coincidental diagnosis of the IBD may delay the progression of the pancreatic disease.
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