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Related Concept Videos

Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy01:30

Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy

Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the colonic...
Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by transmural...
Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
Inflammatory Bowel Disease I: Introduction01:26

Inflammatory Bowel Disease I: Introduction

Inflammatory bowel disease is a group of chronic disorders marked by recurrent inflammation of the gastrointestinal tract due to an abnormal immune response against gut microflora. This leads to tissue damage. The two main forms are Crohn’s disease and ulcerative colitis.Crohn’s DiseaseCrohn’s disease is a relapsing inflammatory disorder that can affect any part of the GI tract, from the mouth to the anus. It involves all layers of the bowel wall (transmural) and shows “skip lesions” in which...
Inflammatory Bowel Disease I: Ulcerative Colitis01:27

Inflammatory Bowel Disease I: Ulcerative Colitis

Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
Inflammatory Bowel Disease IV: Clinical Manifestations01:20

Inflammatory Bowel Disease IV: Clinical Manifestations

Inflammatory bowel disease (IBD) encompasses two major chronic disorders—ulcerative colitis and Crohn’s disease—each characterized by relapsing episodes of gastrointestinal inflammation. Although they share certain clinical features, their patterns of involvement and manifestations differ in ways that aid diagnosis and guide management.Ulcerative ColitisUlcerative colitis is limited to the colon and rectum and involves continuous inflammation of the mucosal layer. The disease course is marked...

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Related Experiment Video

Updated: May 8, 2026

Murine Endoscopy for In Vivo Multimodal Imaging of Carcinogenesis and Assessment of Intestinal Wound Healing and Inflammation
09:42

Murine Endoscopy for In Vivo Multimodal Imaging of Carcinogenesis and Assessment of Intestinal Wound Healing and Inflammation

Published on: August 26, 2014

Small bowel endoscopy in inflammatory bowel disease.

Hirokazu Yamagami1, Kenji Watanabe, Noriko Kamata

  • 1Department of Gastroenterology, Osaka City University Graduate School of Medicine, Osaka, Japan.

Clinical Endoscopy
|August 22, 2013
PubMed
Summary

Small bowel endoscopy aids in early Crohn disease (CD) diagnosis and treatment, detecting inflammation beyond the terminal ileum. This enables timely therapy, preventing disease progression and complications.

Keywords:
Balloon assisted endoscopyCapsule endoscopyCrohn diseaseEndoscopic balloon dilation

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Flexible Colonoscopy in Mice to Evaluate the Severity of Colitis and Colorectal Tumors Using a Validated Endoscopic Scoring System

Published on: October 16, 2013

Investigating Intestinal Inflammation in DSS-induced Model of IBD
08:43

Investigating Intestinal Inflammation in DSS-induced Model of IBD

Published on: February 1, 2012

Related Experiment Videos

Last Updated: May 8, 2026

Murine Endoscopy for In Vivo Multimodal Imaging of Carcinogenesis and Assessment of Intestinal Wound Healing and Inflammation
09:42

Murine Endoscopy for In Vivo Multimodal Imaging of Carcinogenesis and Assessment of Intestinal Wound Healing and Inflammation

Published on: August 26, 2014

Flexible Colonoscopy in Mice to Evaluate the Severity of Colitis and Colorectal Tumors Using a Validated Endoscopic Scoring System
15:49

Flexible Colonoscopy in Mice to Evaluate the Severity of Colitis and Colorectal Tumors Using a Validated Endoscopic Scoring System

Published on: October 16, 2013

Investigating Intestinal Inflammation in DSS-induced Model of IBD
08:43

Investigating Intestinal Inflammation in DSS-induced Model of IBD

Published on: February 1, 2012

Area of Science:

  • Gastroenterology
  • Inflammatory Bowel Disease Research
  • Endoscopic Diagnostics

Background:

  • Crohn disease (CD) is a chronic inflammatory bowel disease impacting the entire GI tract, frequently affecting the large and small intestines.
  • Early diagnosis of CD is crucial for managing chronic inflammation and fibrosis, improving patient outcomes.
  • Conventional ileocolonoscopy has limitations in detecting proximal small bowel or terminal ileum involvement.

Purpose of the Study:

  • To highlight the role of small bowel endoscopy in the differential diagnosis of suspected CD patients.
  • To emphasize the benefits of early detection of active CD for timely therapeutic intervention.
  • To discuss the utility of small bowel endoscopy in evaluating proximal small bowel involvement and treating strictures.

Main Methods:

  • Review of small bowel endoscopy's application in diagnosing and managing Crohn disease.
  • Discussion of endoscopic findings for early CD detection.
  • Comparative analysis with other imaging modalities and consideration of endoscopic surveillance intervals.

Main Results:

  • Small bowel endoscopy facilitates early detection of active CD, enabling prompt treatment before symptom onset.
  • It effectively visualizes inflammatory changes in the proximal small bowel, often missed by conventional methods.
  • Endoscopic balloon dilation (EBD) via small bowel endoscopy offers a treatment option for CD-related small bowel strictures.

Conclusions:

  • Small bowel endoscopy is invaluable for the early diagnosis and management of Crohn disease, particularly for proximal small bowel lesions.
  • It allows for targeted therapy, potentially altering the disease course and preventing complications.
  • Further research is needed to address practical issues like optimal surveillance intervals and long-term outcomes post-EBD.