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Propofol versus Midazolam for Sedation during Esophagogastroduodenoscopy in Children

Ji Eun Oh1, Hae Jeong Lee, Young Hwan Lee

  • 1Department of Internal Medicine, Samsung Changwon Hospital, Sungkyunkwan University School of Medicine, Changwon, Korea.

Clinical Endoscopy
|August 22, 2013
PubMed

Insights

Propofol offers faster recovery for pediatric patients undergoing upper gastrointestinal endoscopy compared to midazolam. Both sedatives are safe for children, with propofol showing quicker recovery times.

Area of Science:

  • Pediatric Gastroenterology
  • Anesthesiology
  • Pharmacology

Background:

  • Sedation is crucial for pediatric esophagogastroduodenoscopy (EGD).
  • Propofol and midazolam are common sedative agents.
  • Evaluating their comparative efficacy and safety in children is important.

Purpose of the Study:

  • To compare the efficacy and safety of propofol versus midazolam for sedation during pediatric EGD.
  • To assess recovery time, procedure length, and need for supportive measures.

Main Methods:

  • Retrospective review of 62 pediatric patients undergoing ambulatory EGD.
  • Comparison of 34 patients receiving propofol with 28 patients receiving midazolam.
  • Analysis of procedure length, recovery time, and vital signs.

Main Results:

  • No significant difference in procedure length between propofol and midazolam groups.
  • Significantly faster recovery time with propofol (30 min) vs. midazolam (59 min).
  • Propofol group showed more stable heart rates and less pain during administration, despite some localized pain.

Conclusions:

  • Propofol provides faster recovery and comparable safety to midazolam for pediatric EGD.
  • Propofol is an effective alternative for sedation in children undergoing upper gastrointestinal endoscopy.
Abstract

Keywords:
ChildEndoscopy, digestive systemMidazolamPropofol

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