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Preparation and Pathogen Inactivation of Double Dose Buffy Coat Platelet Products using the INTERCEPT Blood System
Published on: December 7, 2012
Prophylaxis against exposure to bloodborne pathogens during compounding.
Angie Williams1, William Mixon
1The Compounding Pharmacy Hickory, NC.
Compounding pharmacies face risks from biologic pathogens in blood-derived preparations like autologous eye drops. This report details safe handling practices to prevent occupational exposure to bloodborne pathogens.
Area of Science:
- Occupational Health and Safety
- Pharmaceutical Compounding
- Infectious Disease Control
Background:
- Compounding preparations with blood components, such as autologous eye drops, poses a risk of unintentional exposure to biologic pathogens.
- Handling serum and other blood-derived materials in compounding pharmacies requires stringent safety protocols to protect staff.
Purpose of the Study:
- To describe workplace practices and materials for informing staff on the safe handling of blood or body fluids containing biologic pathogens.
- To provide a prototype standard operating procedure (SOP) for managing occupational exposures to bloodborne pathogens in compounding pharmacies.
Main Methods:
- Review and documentation of existing workplace practices for handling blood-derived materials.
- Development of informational materials for staff training on safe handling procedures.
- Creation of a prototype SOP for managing potential exposures to bloodborne pathogens.
Main Results:
- Identified key practices and materials necessary for safe handling of blood-derived preparations.
- Developed a comprehensive set of guidelines for staff education and training.
- A prototype SOP was created to address potential bloodborne pathogen exposures.
Conclusions:
- Implementing specific workplace practices and providing staff education are crucial for minimizing risks associated with blood-derived preparations.
- The presented prototype plan offers a valuable framework for compounding pharmacists to establish robust safety procedures for bloodborne pathogen exposure management.
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