Prophylaxis against exposure to bloodborne pathogens during compounding
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Updated: May 8, 2026

Preparation and Pathogen Inactivation of Double Dose Buffy Coat Platelet Products using the INTERCEPT Blood System
Published on: December 7, 2012
Angie Williams1, William Mixon
1The Compounding Pharmacy Hickory, NC.
Abstract:
Unintentional exposure to biologic pathogens can occur when preparations that contain blood or its components are compounded. For example, autologous eye drops, which are not commercially manufactured, incorporate serum that must be handled by various staff members in a compounding pharmacy. In this report, we describe workplace practices and materials used to inform our staff members who handle or compound that preparation and other similar formulations about the safe and appropriate handling of blood or body fluids that could contain biologic pathogens. Compounding pharmacists who must develop and implement a standard operating procedure for managing exposures to bloodborne pathogens will find the prototype plan presented in this article of interest.
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