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Related Concept Videos

Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Acne Infection01:27

Acne Infection

Acne is a multifactorial skin condition primarily affecting adolescents and young adults, with a global prevalence estimated to exceed 75% in this demographic. The condition is characterized by the formation of comedones (blackheads and whiteheads), papules, pustules, nodules, and, in severe cases, cysts, particularly in areas rich in sebaceous glands such as the face, neck, chest, and back. The pathogenesis involves increased sebum production, follicular hyperkeratinization, colonization by...
Burn Injuries01:22

Burn Injuries

Burn injuries occur when the skin and underlying tissues are damaged due to exposure to heat, electricity, chemicals, radiation, or friction. They can vary in severity, from minor superficial burns to severe deep burns that can be life-threatening.
The damage results in the death of skin cells, which can lead to a massive loss of fluid. Dehydration, electrolyte imbalance, and renal and circulatory failure follow, which can be fatal. Burn patients are treated with intravenous fluids to offset...
Cancer Therapies02:49

Cancer Therapies

Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
Mutations01:35

Mutations

Mutations are changes in the sequence of DNA. These changes can occur spontaneously or they can be induced by exposure to environmental factors. Mutations can be characterized in a number of different ways: whether and how they alter the amino acid sequence of the protein, whether they occur over a small or large area of DNA, and whether they occur in somatic cells or germline cells.
Chromosomal Alterations Are Large-Scale Mutations
While point mutations are changes in a single nucleotide in...
Physical Methods for Controlling Microbial Growth: Radiation and Filtration01:26

Physical Methods for Controlling Microbial Growth: Radiation and Filtration

Radiation and filtration are essential tools for microbial control, targeting microorganisms through distinct mechanisms. Radiation eliminates microbes by damaging their DNA, either killing them or inhibiting their growth. Based on wavelength, radiation is classified into two types: nonionizing and ionizing radiation.Non-ionizing radiation, such as UV radiation (200–400 nm), is absorbed by DNA, causing defects that effectively disinfect surfaces, air, and water, including safety cabinets.

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Related Experiment Videos

Potential treatments for radiation dermatitis.

Lindsay Corsini1

  • 1Drug Warehourse, a Subsidiary of USA Drug, Tulsa, Oklahoma.

International Journal of Pharmaceutical Compounding
|August 23, 2013
PubMed
Summary

Radiation therapy can cause painful skin side effects. Compounding pharmacists can create personalized treatments to alleviate radiation burns and improve cancer patients

Area of Science:

  • Oncology
  • Dermatology
  • Pharmaceutical Sciences

Background:

  • Radiation therapy, a cornerstone of cancer treatment, often leads to significant skin toxicity, impacting patient quality of life.
  • Radiation-induced skin reactions range from dryness and itching to severe peeling and blistering, necessitating effective management strategies.
  • Current management of radiation burns relies on supportive care, with limited options for individualized therapeutic interventions.

Purpose of the Study:

  • To explore the role of compounding pharmacists in managing radiation therapy-induced skin toxicities.
  • To discuss various agents and formulations utilized by compounding pharmacists for radiation burn treatment.
  • To highlight the collaborative approach between pharmacists, physicians, and patients in optimizing care for cancer patients undergoing radiation.

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Main Methods:

  • Review of medicinal agents and compounding techniques applicable to radiation dermatitis.
  • Discussion of formulation strategies for topical and systemic treatments.
  • Emphasis on personalized medicine approaches tailored to individual patient needs and reactions.

Main Results:

  • Compounding pharmacists can offer customized solutions to mitigate radiation-induced skin damage.
  • A variety of agents, including emollients, anti-inflammatories, and barrier protectants, can be formulated for targeted relief.
  • Personalized compounding enhances patient comfort and adherence to cancer treatment regimens.

Conclusions:

  • Compounding pharmacy plays a vital role in alleviating the burdensome side effects of radiation therapy.
  • Collaborative efforts ensure that cancer patients receive individualized care to manage skin toxicity effectively.
  • Optimized management of radiation burns through compounding can significantly improve the quality of life during cancer treatment.