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Published on: July 28, 2022
[Advances in medical care for extremely low birth weight infants worldwide]
1Department of Pediatrics, Shenzhen Maternity and Child Health Care Hospital, Southern Medical University, Shenzhen, Guangdong 518028, China. zhangqianshen2005@163.com.
Insights
Advances in neonatal medicine improve survival for extremely low birth weight infants. However, ongoing research addresses their significant short- and long-term health challenges and ethical considerations.
Area of Science:
- Neonatal Medicine
- Perinatology
- Pediatric Neurology
Context:
- Neonatal intensive care has significantly reduced mortality for extremely low birth weight (ELBW) infants.
- Despite survival gains, ELBW infants face substantial short- and long-term health complications.
Purpose:
- To review recent advancements in the medical care of ELBW infants.
- To discuss survival rates, ethical considerations, and morbidity in ELBW infants.
- To provide a domestic and international overview of ELBW infant care.
Summary:
- Recent decades show dramatic progress in neonatal medicine, improving ELBW infant survival rates.
- Key morbidities include intraventricular hemorrhage, periventricular leukomalacia, necrotizing enterocolitis, bronchopulmonary dysplasia, retinopathy of prematurity, and neurodevelopmental issues.
- The review covers survival, ethical dilemmas, and short/long-term morbidities in ELBW infants, referencing global and domestic data.
Impact:
- Improved understanding of ELBW infant outcomes and care strategies.
- Highlights the critical need for continued research into managing complex neonatal conditions.
- Informs clinical practice and policy regarding the care of premature infants.
Abstract:
Dramatic advances in neonatal medicine over recent decades have resulted in decreased mortality and morbidity rates for extremely low birth weight infants. However, the survival of these infants is associated with short- and long-term morbidity, including severe intraventricular hemorrhage, periventricular leukomalacia, nosocomial infection and necrotizing enterocolitis, bronchopulmonary dysplasia, retinopathy of prematurity and adverse long-term neurodevelopmental sequelae. This article reviewed the latest advances in the medical care for extremely low birth weight infants including survival rate, ethical issues and short- and long-term morbidity, domestically and abroad.
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