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Association of interankle systolic blood pressure difference with peripheral vascular disease and left ventricular

Ho-Ming Su1, Tsung-Hsien Lin, Po-Chao Hsu

  • 1Division of Cardiology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.

American Journal of Hypertension
|August 23, 2013
PubMed

Insights

An elevated interankle systolic blood pressure difference is linked to peripheral vascular disease and increased left ventricular mass index. This measurement aids in identifying at-risk patients beyond standard clinical assessments.

Area of Science:

  • Cardiology
  • Vascular Medicine
  • Diagnostic Imaging

Background:

  • Interankle systolic blood pressure (SBP) difference is a known mortality risk factor.
  • The relationship between interankle SBP difference and specific vascular and cardiac parameters requires further investigation.

Purpose of the Study:

  • To explore the association between interankle SBP difference and ankle-brachial index (ABI), brachial-ankle pulse wave velocity (baPWV), and echocardiographic parameters.
  • To determine if interankle SBP difference can improve the prediction of peripheral vascular disease and left ventricular hypertrophy.

Main Methods:

  • Simultaneous measurement of 4-limb blood pressures in 1,059 patients undergoing echocardiography.
  • Multivariate forward analysis to identify factors associated with an interankle SBP difference ≥ 15mm Hg.

Main Results:

  • Ankle-brachial index < 0.9, high brachial-ankle pulse wave velocity, and increased left ventricular mass index were independently associated with an interankle SBP difference ≥ 15mm Hg.
  • An interankle SBP difference ≥ 15mm Hg significantly improved the prediction of ABI < 0.9 and increased left ventricular mass index when added to clinical features.

Conclusions:

  • Ankle-brachial index < 0.9, high brachial-ankle pulse wave velocity, and increased left ventricular mass index are independently linked to a significant interankle SBP difference.
  • Measuring interankle SBP difference provides additional value in identifying patients with peripheral vascular disease and increased left ventricular mass index.
Abstract

Keywords:
ankle-brachial indexblood pressurebrachial-ankle pulse wave velocityhypertensioninterankle systolic blood pressure difference.left ventricular mass index

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