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Related Concept Videos

Mesenchymal Stem Cells01:19

Mesenchymal Stem Cells

Mesenchymal stem cells (MSCs) are adult stem cells that can differentiate into most connective tissue cell types, except for hematopoietic cells, depending upon the source of MSCs. For example, bone-marrow-derived MSCs (BM-MSCs) can differentiate into osteocytes, hepatocytes, and pancreatic and neuronal cells. MSCs can be isolated from various sources such as bone marrow, placenta, adipose tissue, teeth, and Wharton’s jelly, a gelatinous substance in the umbilical cord. The ease of their access...

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Induction of Mesenchymal-Epithelial Transitions in Sarcoma Cells
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Induction of Mesenchymal-Epithelial Transitions in Sarcoma Cells

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Mesenchymal chondrosarcoma: a case report.

Dang Vu Nguyen1, Ahmad Sobri Muda, Yazmin Yaacob

  • 1Department of Radiology, Universiti Kebangsaan Malaysia Medical Centre, Jalan Yaacob Latif, Bandar Tun Razak, Cheras, 56000 Kuala Lumpur, Malaysia.

The Malaysian Journal of Medical Sciences : MJMS
|August 23, 2013
PubMed
Summary
This summary is machine-generated.

Mesenchymal chondrosarcoma, a rare cancer, requires surgical excision. Preoperative angioembolization may reduce surgical bleeding, improving complete tumor removal rates for better outcomes.

Keywords:
extraskeletalmesenchymal chondrosarcomatherapeutic embolization

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Area of Science:

  • Oncology
  • Surgical Oncology
  • Radiology

Background:

  • Mesenchymal chondrosarcoma is a rare malignancy with a poor prognosis.
  • Effective treatment strategies remain challenging.
  • Surgical resection is a cornerstone of management.

Purpose of the Study:

  • To highlight the importance of surgical excision in mesenchymal chondrosarcoma.
  • To explore the role of adjuvant therapies like radiotherapy and chemotherapy.
  • To evaluate the utility of imaging and preoperative embolization in surgical planning and outcomes.

Main Methods:

  • Review of existing literature on mesenchymal chondrosarcoma treatment.
  • Analysis of the role of imaging modalities in diagnosis and planning.
  • Assessment of the potential benefits of angioembolization in surgical management.

Main Results:

  • Wide or radical excision is critical for treatment.
  • Radiotherapy and chemotherapy efficacy is not conclusively established.
  • Angioembolization may serve as a prophylactic measure against intraoperative bleeding.

Conclusions:

  • Complete resection is crucial for mesenchymal chondrosarcoma.
  • Preoperative angioembolization can facilitate complete resection by controlling bleeding.
  • Further research is needed to define the role of adjuvant therapies.