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Related Concept Videos

Neuroplasticity01:01

Neuroplasticity

Neuroplasticity reflects the brain's remarkable capacity to adapt and evolve, responding dynamically to learning, experiences, or injury by reorganizing its neural circuitry. This reorganization involves creating new neural connections and refining old ones through a series of biological processes that contribute to the brain's lifelong development and adaptability.
Spinal Nerves: Plexus I01:22

Spinal Nerves: Plexus I

Nerve plexuses are networks of interlacing nerves that serve as communication hubs to distribute and organize nerve action across various body regions. The nerve plexuses are organized into the cervical plexus located in the neck region, brachial plexus in the shoulder area, lumbar plexus found in the lower back, sacral plexus situated in the pelvis, and coccygeal plexus located in the coccygeal region.
The Cervical Plexus
The cervical plexus, formed by the anterior rami of the first four...

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Related Experiment Video

Updated: May 8, 2026

Structured Motor Rehabilitation After Selective Nerve Transfers
09:34

Structured Motor Rehabilitation After Selective Nerve Transfers

Published on: August 15, 2019

Motor cortex neuroplasticity following brachial plexus transfer.

Stefan Dimou1, Michael Biggs, Michael Tonkin

  • 1Sydney Medical School, The University of Sydney , Sydney, NSW , Australia.

Frontiers in Human Neuroscience
|August 23, 2013
PubMed
Summary

Adult brain plasticity enables functional recovery after surgery. This case study shows neuroimaging revealing sensorimotor cortex changes and reduced phantom limb pain following brachial plexus surgery.

Keywords:
MRIbrachial plexus transfermotor cortexneuroimagingphantom limb

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Last Updated: May 8, 2026

Structured Motor Rehabilitation After Selective Nerve Transfers
09:34

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Published on: August 15, 2019

A Mouse Model of Direct Anastomosis via the Prespinal Route for Crossing Nerve Transfer Surgery
05:56

A Mouse Model of Direct Anastomosis via the Prespinal Route for Crossing Nerve Transfer Surgery

Published on: October 19, 2021

Area of Science:

  • Neuroscience
  • Clinical Neurology
  • Rehabilitation Medicine

Background:

  • Cortical plasticity, the brain's ability to reorganize, continues into adulthood.
  • This adaptability is crucial for functional recovery and compensation after injury or surgery.
  • Understanding adult plasticity informs therapeutic strategies for neurological conditions.

Purpose of the Study:

  • To investigate cortical plasticity in an adult patient undergoing brachial plexus transfer surgery.
  • To observe neuroimaging changes in sensorimotor cortex activation post-surgery.
  • To assess the impact of surgery on phantom limb pain (PLP).

Main Methods:

  • Case study of a 27-year-old female patient.
  • Utilized neuroimaging techniques (fMRI implied) to observe brain activity.
  • Assessed motor task performance (elbow flexion, finger tapping) and PLP levels.

Main Results:

  • Observed functional topographical expansion in the sensorimotor cortex.
  • Bilateral sensorimotor cortex activation during elbow flexion; differential activation during finger tapping.
  • Significant reduction in phantom limb pain reported post-surgery.

Conclusions:

  • Adult cortical plasticity supports functional recovery and reorganization after nerve transfer surgery.
  • Increased sensorimotor cortex activation correlates with improved limb mobility.
  • Brachial plexus transfer surgery can effectively reduce phantom limb pain.