Jove
Visualize
Contact Us

Related Concept Videos

Genomic DNA in Eukaryotes00:58

Genomic DNA in Eukaryotes

53.3K
Eukaryotes have large genomes compared to prokaryotes. To fit their genomes into a cell, eukaryotic DNA is packaged extraordinarily tightly inside the nucleus. To achieve this, DNA is tightly wound around proteins called histones, which are packaged into nucleosomes that are joined by linker DNA and coil into chromatin fibers. Additional fibrous proteins further compact the chromatin, which is recognizable as chromosomes during certain phases of cell division.
53.3K
Genomics02:02

Genomics

41.0K
Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
41.0K
Genome Annotation and Assembly03:36

Genome Annotation and Assembly

21.1K
The genome refers to all of the genetic material in an organism. It can range from a few million base pairs in microbial cells to several billion base pairs in many eukaryotic organisms. Genome assembly refers to the process of taking the DNA sequencing data and putting it all back together in a correct order to create a close representation of the original genome. This is followed by the identification of functional elements on the newly assembled genome, a process called genome annotation.
21.1K
DNA as a Genetic Template02:05

DNA as a Genetic Template

28.2K
Two structural features of the DNA molecule provide a basis for the mechanisms of heredity: the four nucleotide bases and its double-stranded nature. The Watson-Crick model of double-helical DNA structure, proposed in 1952, drew heavily upon the X-ray crystallography work of researchers Rosalind Franklin and Maurice Wilkins. Watson, Crick, and Wilkins jointly received the Nobel Prize in Physiology or Medicine for their work in 1962. Franklin was, controversially, excluded from the prize for...
28.2K
DNA as a Genetic Template02:05

DNA as a Genetic Template

9.6K
No description available
9.6K
Genetic Material01:20

Genetic Material

3.8K
Within the human body, a complex and detailed system of trillions of cells works in unison to sustain life. Each cell houses a nucleus, which contains 46 chromosomes divided into 23 pairs. Chromosomes are highly coiled structures made of the genetic material DNA. These chromosomes are essential carriers of genetic information, with half inherited from the mother through her egg and the other half from the father's sperm, combining to create the unique genetic makeup of an individual.
3.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Autism and cancer risk.

Autism research : official journal of the International Society for Autism Research·2011
Same author

High dynamic range CMOS image sensors in biomedical applications.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference·2007
Same author

Imbalanced genomic imprinting in brain development: an evolutionary basis for the aetiology of autism.

Journal of evolutionary biology·2006
Same author

The evolution of inquilinism, host-plant use and mitochondrial substitution rates in Tamalia gall aphids.

Journal of evolutionary biology·2003
Same author

Storage capacity of non-monotonic neurons.

Neural networks : the official journal of the International Neural Network Society·2003
Same author

[Skin versus mesh in the treatment of laparoceles].

Minerva chirurgica·1992
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Feb 20, 2026

Genome-Wide CRISPR Screen for Unveiling Radiosensitive and Radioresistant Genes
08:32

Genome-Wide CRISPR Screen for Unveiling Radiosensitive and Radioresistant Genes

Published on: May 23, 2025

1.3K

What is a genome?

A Stencel1, B Crespi

  • 1Institute of Environmental Sciences, Jagiellonian University,Gronostajowa 7, 30-387 Kraków, Poland.

Molecular Ecology
|August 23, 2013
PubMed
Summary
This summary is machine-generated.

Researchers propose an evolutionary definition of the genome, defining it as a lineage's genetic material favoring similar phenotypes. This new framework offers fresh perspectives for genomics research.

More Related Videos

Author Spotlight: Investigating the Role of Repetitive DNA Misregulation in Cancer Initiation and Immunotherapy Resistance
04:58

Author Spotlight: Investigating the Role of Repetitive DNA Misregulation in Cancer Initiation and Immunotherapy Resistance

Published on: December 13, 2024

4.2K
Genome-wide Surveillance of Transcription Errors in Eukaryotic Organisms
09:30

Genome-wide Surveillance of Transcription Errors in Eukaryotic Organisms

Published on: September 13, 2018

10.0K

Related Experiment Videos

Last Updated: Feb 20, 2026

Genome-Wide CRISPR Screen for Unveiling Radiosensitive and Radioresistant Genes
08:32

Genome-Wide CRISPR Screen for Unveiling Radiosensitive and Radioresistant Genes

Published on: May 23, 2025

1.3K
Author Spotlight: Investigating the Role of Repetitive DNA Misregulation in Cancer Initiation and Immunotherapy Resistance
04:58

Author Spotlight: Investigating the Role of Repetitive DNA Misregulation in Cancer Initiation and Immunotherapy Resistance

Published on: December 13, 2024

4.2K
Genome-wide Surveillance of Transcription Errors in Eukaryotic Organisms
09:30

Genome-wide Surveillance of Transcription Errors in Eukaryotic Organisms

Published on: September 13, 2018

10.0K

Area of Science:

  • Genomics
  • Evolutionary Biology
  • Conceptual Frameworks

Background:

  • The field of genomics is rapidly advancing.
  • Existing conceptualizations of the 'genome' lack explicit, coherent, and useful frameworks.
  • There is a need for refined definitions to guide research.

Purpose of the Study:

  • To develop and apply an evolutionary conceptualization of the genome.
  • To extend George C. Williams' evolutionary definition of a gene.
  • To provide novel perspectives on genome functions, boundaries, and evolution.

Main Methods:

  • Developing a conceptual framework based on evolutionary principles.
  • Extending the evolutionary definition of a gene to the genome.
  • Applying this conceptualization to theoretical and empirical genomics.

Main Results:

  • An evolutionary genome is conceptualized as a set of genetic material within a lineage.
  • This genetic material tends to favor the same or similar phenotypes due to common interests.
  • The proposed framework offers new insights into genome properties.

Conclusions:

  • The evolutionary conceptualization of the genome provides a useful framework for genomics research.
  • This definition clarifies genome functions, boundaries, and evolutionary dynamics.
  • It is expected to guide future theoretical and empirical studies in genomics.