Related Experiment Video
Updated: Feb 20, 2026

Genome-Wide CRISPR Screen for Unveiling Radiosensitive and Radioresistant Genes
Published on: May 23, 2025
What is a genome?
1Institute of Environmental Sciences, Jagiellonian University,Gronostajowa 7, 30-387 Kraków, Poland.
Abstract:
The field of genomics is expanding rapidly, yet the meanings of the word ‘genome’ have yet to be conceptualized in explicit, coherent and useful frameworks. We develop and apply an evolutionary conceptualization of the genome,which represents a logical extension of the evolutionary definition of a gene developed by George C.Williams. An evolutionary genome thus represents a set of genetic material, in a lineage, that due to common interests tends to favour the same or similar phenotypes.This conceptualization provides novel perspectives on genome functions, boundaries and evolution, which should help to guide theoretical and empirical genomics research.
Related Concept Videos
Genomic DNA in Eukaryotes
Genomics
Genome Annotation and Assembly
DNA as a Genetic Template
DNA as a Genetic Template
Genetic Material

