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Updated: May 8, 2026

A 3D Organotypic Melanoma Spheroid Skin Model
Published on: May 18, 2018
Late recurrence of malignant melanoma mimicking primary peritoneal cancer
M Sano1, Y Hashiguchi, T Yasui
1Department of Obstetrics and Gynecology, Osaka City University, Graduate School of Medicine, Osaka, Japan.
Background:
Malignant melanoma is an extremely malignant tumor with an unpredictable metastatic profile with variable periods of remission.
Case:
A 41-year-old woman presented with recurrent malignant melanoma which had clinical features of an acute state mimicking primary peritoneal cancer. The case was an unusual recurrence of malignant melanoma occurring seven years after diagnosis and treatment of malignant melanoma in the patient's arm. The diagnosis was established postoperatively by immunohistochemistry.
Conclusion:
A variety of imaging methods and pathological methods, including an exploratory laparotomy, may be necessary in cases of patients suspecting primary peritoneal cancer with a previous history of melanoma with possible metastatic dissemination. Urgent diagnosis and treatment of these patients seems to be critical.