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Updated: May 8, 2026

Establishment and Evaluation of a Risk Prediction Model for Pathological Escalation of Gastric Low-Grade Intraepithelial Neoplasia
Published on: February 16, 2024
[Epidemiology of H. pylori infection and gastric mucosal atrophy]
1Department of Public Health, Aichi Medical University School of Medicine.
Abstract:
Progress in sanitary conditions, especially development of clean water supply for these 50 years has been reducing prevalence of Helicobacter pylori infection in Japan. The reduction in corporation with a less intake of highly salted foods and probably infection at later ages decreases prevalence and/or severity of gastric mucosal atrophy. Consequently, incidence of gastric cancer has been decreasing. However, it was unveiled that those with H. pylori infection and gastric mucosal atrophy have high risk of gastric cancer even after successful eradication of the infection, which still remains as a problem.
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