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Updated: May 8, 2026

Gastric Mucosa Quantitative Polymerase Chain Reaction Analysis for Detecting Helicobacter pylori and Antibiotic Resistance
Published on: March 7, 2025
[Transmission route of H. pylori]
Masumi Okuda1, Tomohiro Tachikawa, Kohei Maekawa
1Department of Pediatrics, Sasayama Medical Center, Hyogo College of Medicine.
Abstract:
The incidence of Helicobacter pylori (H. pylori) infection is rapidly decreased in Japan. H. pylori infection is mainly acquired in the first 2 years life and the risk of infection declines rapidly after 5 years of age. Person-to-person transmission in the family appears to be the predominant and in the population with low prevalence, several studies showed the infected mother is likely to be the main source of the infection. H. pylori can be detected from vomitus, saliva and cathartic stools and the possibility of source of infection. Waterborne infection is unlikely in the developed countries.
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