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Updated: May 8, 2026

Gastric Mucosa Quantitative Polymerase Chain Reaction Analysis for Detecting Helicobacter pylori and Antibiotic Resistance
Published on: March 7, 2025
[H. pylori infection and lifestyle related diseases]
Daisuke Chinda1, Tadashi Shimoyama
1Department of Gastroenterology, Hirosaki University Graduate School of Medicine.
Abstract:
The association between Helicobacter pylori infection and lifestyle related diseases was examined in a health survey. The results suggested that 1) infection of H. pylori would accelerate the progress of atherosclerosis in elderly men who smoke, 2) severe atrophic gastritis caused by H. pylori infection would have a significant association with the decrease in serum lipid level, 3) H. pylori infection was a decreased risk for tooth loss in healthy men, and 4) H. pylori infection was not associated with osteopenia in elderly. Since, clinical features, such as proportion of cagA-positive strains and frequency of severe atrophic gastritis in elderly are different between Western populations and Japanese, further studies based on Japanese patients are required to determine the association between H. pylori infection and lifestyle related diseases.
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