Related Experiment Video
Updated: May 8, 2026
10:39
Qualitative and Quantitative Validation of Tools with Rating Scales Aimed at Assessing the Quality of University Service-Learning
Published on: August 29, 2025
Strategies to assess the validity of recommendations: a study protocol
Laura Martínez García1, Andrea Juliana Sanabria, Ignacio Araya
1Iberoamerican Cochrane Centre- Biomedical Research Institute Sant Pau IIB Sant Pau, Barcelona, Spain. laura.martinez.garcia@cochrane.es
Implementation Science : IS
|August 24, 2013
Summary
Clinical practice guidelines (CPGs) quickly become outdated. This study assesses recommendation obsolescence and evaluates efficient search strategies for updating CPGs, aiming to improve evidence-based healthcare.
Area of Science:
- Health Services Research
- Evidence-Based Medicine
- Clinical Guideline Development
Background:
- Clinical practice guidelines (CPGs) require regular updates to remain valid.
- Limited research exists on CPG recommendation obsolescence and efficient updating strategies.
- This study addresses critical questions regarding CPG validity and maintenance.
Purpose of the Study:
- Determine the average time for CPG recommendations to become outdated.
- Compare the performance of two restricted search strategies for updating CPGs.
- Evaluate the feasibility of regular monitoring and updating strategies.
Main Methods:
- Analysis of 14 CPGs developed between 2008-2009, stratified by topic and year.
- Development of a validity assessment strategy including expert surveys and updated literature searches.
- Implementation and comparison of two novel search strategies: McMaster PLUS and Restrictive Search (ReSe).
Main Results:
- Survival analysis using Kaplan-Meier method to assess recommendation obsolescence.
- Log-rank test to analyze differences in obsolescence based on guideline characteristics.
- Evaluation of key reference retrieval using PLUS and ReSe strategies.
Conclusions:
- The project will provide guidance on the timeliness of CPG recommendation updates.
- Novel restrictive search strategies will be assessed for efficiency and rigor in CPG updating.
- Findings will inform more regular and effective CPG monitoring and maintenance practices.
Related Concept Videos
01:23Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches
Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast, controlled...
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast, controlled...
01:15Bioequivalence Experimental Study Designs: Repeated Measures, Cross-Over, Carry-Over, and Latin Square Designs
Bioequivalence experimental study designs play a pivotal role in testing the effectiveness of various treatments. Key among these are the repeated measures, cross-over, carry-over, and Latin square designs. In the repeated measures design, each subject receives all treatments, allowing for temporal comparisons. This type of design is useful in reducing variability but requires careful planning to avoid bias.The cross-over design, an economical method, involves sequential administration of...
01:29Reliability and Validity
Reliability and validity are two important considerations that must be made with any type of data collection. Reliability refers to the ability to consistently produce a given result. In the context of psychological research, this would mean that any instruments or tools used to collect data do so in consistent, reproducible ways.
01:03Data Validation
Data validation is an essential part of a comprehensive assessment. Validation is confirming or verifying and opening the door to gathering more assessment data as it clarifies vague or unclear data. The process of checking and verifying the collected information is called data validation. The primary purpose of data validation is to ensure data is as free from error, bias, and misinterpretation as possible.
Nursing assessment guides are generally based on holistic models rather than medical...
Nursing assessment guides are generally based on holistic models rather than medical...
01:20Study Designs in Epidemiology
Epidemiological study designs are fundamental tools for investigating the distribution, determinants, and control of health conditions in populations. They help researchers understand the relationships between exposures and outcomes, and they broadly fall into two categories: "observational" and "experimental" studies.
Observational studies are those where the researcher does not intervene but rather observes natural variations. They include cross-sectional, cohort, and case-control studies.
Observational studies are those where the researcher does not intervene but rather observes natural variations. They include cross-sectional, cohort, and case-control studies.
01:25Strategies for Assessing and Addressing Confounding
Confounding is a critical issue in epidemiological studies, often leading to misleading conclusions about associations between exposures and outcomes. It occurs when the relationship between the exposure and the outcome is mixed with the effects of other factors that influence the outcome. Given that, addressing confounding is of high importance for drawing accurate inferences in research.
Confounding can be addressed at both the design phase of a study and through analytical methods after data...
Confounding can be addressed at both the design phase of a study and through analytical methods after data...