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Updated: May 8, 2026

Upper-extremity Approach for Secondary Access in Transfemoral Transcatheter Aortic Valve Implantation
Published on: August 8, 2025
Management of vascular access in transcatheter aortic valve replacement: part 2: Vascular complications
Stefan Toggweiler1, Jonathon Leipsic, Ronald K Binder
1St. Paul's Hospital, University of British Columbia, Vancouver, British Columbia, Canada.
Insights
Recognizing and managing vascular complications, particularly iliofemoral ones in transcatheter aortic valve implantation, is crucial for interventional cardiologists. Endovascular techniques offer less invasive options for managing arterial injuries and ruptures.
Area of Science:
- Cardiology
- Interventional Cardiology
- Vascular Surgery
Background:
- Vascular complications are a significant concern in interventional cardiology procedures.
- Transfemoral transcatheter aortic valve implantation (TAVI) is associated with frequent iliofemoral complications.
- Predictors include small vessel size, calcification, and procedural experience.
Purpose of the Study:
- To outline the recognition and management strategies for vascular complications during interventional cardiology procedures.
- To highlight the prevalence and predictors of iliofemoral complications in TAVI.
- To discuss evolving treatment options, including endovascular techniques.
Main Methods:
- Review of current literature and clinical practices for managing vascular complications.
- Analysis of predictors for iliofemoral complications in TAVI.
- Description of treatment algorithms for various arterial injuries and ruptures.
Main Results:
- Iliofemoral complications are the most common vascular issues in transfemoral TAVI.
- Small vessel dimensions, calcification, and center experience are key predictors.
- Endovascular techniques provide less invasive alternatives to surgical reconstruction for arterial injuries.
Conclusions:
- Effective management of vascular complications requires prompt recognition and appropriate intervention.
- Endovascular approaches are increasingly viable for treating TAVI-related arterial injuries.
- Awareness of complications associated with alternative access routes is also important.
Abstract:
The interventional cardiologist must be able to recognize and manage potential vascular complications. Iliofemoral complications are the most frequent vascular complications in transfemoral transcatheter aortic valve implantation. Small vessel dimensions, moderate or severe calcification, and center experience are the major predictors. The traditional treatment for injured arteries has been surgical reconstruction, but endovascular techniques may allow for less invasive but effective management of arterial injuries. Dissection may be treated with prolonged balloon inflation or deployment of a self-expanding or balloon-expandable stent or a surgical graft. Iliofemoral rupture is a serious complication that may lead to retroperitoneal bleeding that can be unrecognized. Rapid insertion of a dilator or sheath or an occlusive balloon is used to achieve hemostasis. Prolonged balloon inflation or implantation of a covered stent or surgical repair should then be considered. Treatment options for failed percutaneous closure include prolonged manual compression, balloon angioplasty, stent implantation, and surgery. Aortic complications are rare, but serious complications are associated with a high mortality rate, even if emergent surgery is performed. There are specific vascular complications associated with alternative access routes such as transapical and transaxillary and direct aortic access.
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