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Related Experiment Videos

An electric artificial heart for clinical use.

W S Pierce1, G Rosenberg, A J Snyder

  • 1Department of Surgery, Milton S. Hershey Medical Center, Pennsylvania State University, Hershey 17033.

Annals of Surgery
|September 1, 1990
PubMed
Summary

An implantable electric heart pump shows promise for patients with end-stage heart disease. Early calf studies demonstrate feasibility, with ongoing research addressing component longevity and complication mitigation for future therapeutic use.

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Area of Science:

  • Biomedical Engineering
  • Cardiovascular Surgery
  • Medical Device Development

Background:

  • Current treatments for end-stage heart disease are limited.
  • Technological advancements enable the development of implantable artificial hearts.

Purpose of the Study:

  • To assess the feasibility and performance of a novel, electrically powered artificial heart.
  • To evaluate the long-term viability of artificial heart implantation in animal models.

Main Methods:

  • Development of a compact, dual pusher plate electric heart with polyurethane ventricles.
  • Utilized a microprocessor control system for beat rate regulation and output balance.
  • Conducted bench studies up to 1 year and implantation in 18 calves.

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Main Results:

  • The electric heart demonstrated functional capacity in bench studies and calf models.
  • The longest survival period in calves reached over 7 months.
  • Identified component failure, thromboembolism, and bleeding as primary complications.

Conclusions:

  • The electrically powered artificial heart is a feasible option for end-stage heart disease.
  • Further research is needed to overcome component failure and thromboembolic complications for prolonged use.
  • This technology represents a potential future therapeutic option for patients with severe heart failure.