Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Protein Networks02:26

Protein Networks

An organism can have thousands of different proteins, and these proteins must cooperate to ensure the health of an organism. Proteins bind to other proteins and form complexes to carry out their functions. Many proteins interact with multiple other proteins creating a complex network of protein interactions.
These interactions can be represented through maps depicting protein-protein interaction networks, represented as nodes and edges. Nodes are circles that are representative of a protein,...
Protein Networks02:26

Protein Networks

An organism can have thousands of different proteins, and these proteins must cooperate to ensure the health of an organism. Proteins bind to other proteins and form complexes to carry out their functions. Many proteins interact with multiple other proteins creating a complex network of protein interactions.
These interactions can be represented through maps depicting protein-protein interaction networks, represented as nodes and edges. Nodes are circles that are representative of a protein,...
Model Approaches for Pharmacokinetic Data: Distributed Parameter Models01:06

Model Approaches for Pharmacokinetic Data: Distributed Parameter Models

Pharmacokinetic models are mathematical constructs that represent and predict the time course of drug concentrations in the body, providing meaningful pharmacokinetic parameters. These models are categorized into compartment, physiological, and distributed parameter models.
The distributed parameter models are specifically designed to account for variations and differences in some drug classes. This model is particularly useful for assessing regional concentrations of anticancer or...
Molecular Models02:00

Molecular Models

Physical models representing molecular architectures of chemical compounds play essential roles in understanding chemistry. The use of molecular models makes it easier to visualize the structures and shapes of atoms and molecules.
Synthetic Biology02:55

Synthetic Biology

Synthetic biology is an interdisciplinary science that involves using principles from disciplines such as engineering, molecular biology, cell biology, and systems biology. It involves remodeling existing organisms from nature or constructing completely new synthetic organisms for applications such as protein or enzyme production, bioremediation, value-added macromolecule production, and the addition of desirable traits to crops, to name a few.
Golden rice
Golden rice is a genetically modified...
Biostatistics: Overview01:20

Biostatistics: Overview

Biostatistics plays a crucial role in understanding and analyzing data in healthcare and biology. Biostatisticians conduct experiments, gather evidence, and draw meaningful conclusions using statistical methods and techniques. Different variables form the foundation of biostatistical analysis, allowing researchers to understand and interpret data effectively. These variables are classified into different types, each serving a specific purpose in statistical analysis.
Discrete variables are...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Drug Development.

Alzheimer's & dementia : the journal of the Alzheimer's Associationยท2025
Same author

A machine learning-based investigation of integrin expression patterns in cancer and metastasis.

Scientific reportsยท2025
Same author

Discovery of Potent and Brain-Penetrant Bicyclic NLRP3 Inhibitors with Peripheral and Central In Vivo Activity.

Journal of medicinal chemistryยท2025
Same author

P2X7R antagonism suppresses long-lasting brain hyperexcitability following traumatic brain injury in mice.

Theranosticsยท2025
Same author

A Machine Learning-Based Investigation of Integrin Expression Patterns in Cancer and Metastasis.

bioRxiv : the preprint server for biologyยท2024
Same author

Characterization of tritiated JNJ-GluN2B-5 (3-[<sup>3</sup>H] 1-(azetidin-1-yl)-2-(6-(4-fluoro-3-methyl-phenyl)pyrrolo[3,2-b]pyridin-1-yl)ethanone), a high affinity GluN2B radioligand with selectivity over sigma receptors.

Journal of neurochemistryยท2024
Same journal

3DICE: Interpretable 3D Cross-Modal Learning for Drug-Target Interaction Prediction and Large-Scale Drug Discovery.

Bioinformatics (Oxford, England)ยท2026
Same journal

KASSPer: Kinase Active Site Structure Prediction using Protein and Ligand Language Models and Its Application to Virtual Screening.

Bioinformatics (Oxford, England)ยท2026
Same journal

IDR searcher: a search engine solution for public image resources.

Bioinformatics (Oxford, England)ยท2026
Same journal

KCFtools: Rapid alignment-free method for introgression screening and GWAS using k-mer profiles.

Bioinformatics (Oxford, England)ยท2026
Same journal

Meta2DB: Curated shotgun metagenomic feature sets and metadata for health state prediction.

Bioinformatics (Oxford, England)ยท2026
Same journal

conMItion: an R package adjusting confounding factors for associations in multi-omics.

Bioinformatics (Oxford, England)ยท2026
See all related articles

Related Experiment Video

Updated: May 8, 2026

A Web Tool for Generating High Quality Machine-readable Biological Pathways
08:01

A Web Tool for Generating High Quality Machine-readable Biological Pathways

Published on: February 8, 2017

Bayesian Network Webserver: a comprehensive tool for biological network modeling.

Jesse D Ziebarth1, Anindya Bhattacharya, Yan Cui

  • 1Department of Microbiology, Immunology and Biochemistry and Center for Integrative and Translational Genomics, University of Tennessee Health Science Center, Memphis, TN 38163, USA.

Bioinformatics (Oxford, England)
|August 24, 2013
PubMed
Summary
This summary is machine-generated.

The Bayesian Network Webserver (BNW) provides a platform for comprehensive network modeling of biological data, enabling users to analyze complex relationships in systems genetics. BNW supports hybrid datasets and incorporates prior knowledge for robust network structure learning and hypothesis generation.

More Related Videos

Inherent Dynamics Visualizer, an Interactive Application for Evaluating and Visualizing Outputs from a Gene Regulatory Network Inference Pipeline
10:44

Inherent Dynamics Visualizer, an Interactive Application for Evaluating and Visualizing Outputs from a Gene Regulatory Network Inference Pipeline

Published on: December 7, 2021

Related Experiment Videos

Last Updated: May 8, 2026

A Web Tool for Generating High Quality Machine-readable Biological Pathways
08:01

A Web Tool for Generating High Quality Machine-readable Biological Pathways

Published on: February 8, 2017

Inherent Dynamics Visualizer, an Interactive Application for Evaluating and Visualizing Outputs from a Gene Regulatory Network Inference Pipeline
10:44

Inherent Dynamics Visualizer, an Interactive Application for Evaluating and Visualizing Outputs from a Gene Regulatory Network Inference Pipeline

Published on: December 7, 2021

Area of Science:

  • Computational biology
  • Systems genetics
  • Bioinformatics

Background:

  • Biological datasets often contain mixed discrete and continuous variables.
  • Understanding relationships between variables is crucial in systems genetics.
  • Existing platforms may lack comprehensive network modeling capabilities for hybrid datasets.

Purpose of the Study:

  • Introduce the Bayesian Network Webserver (BNW) as a platform for network modeling.
  • Facilitate the analysis of systems genetics and other biological datasets.
  • Enable users to learn network structures and explore variable relationships.

Main Methods:

  • BNW allows seamless data uploading and network structure learning.
  • The platform supports hybrid datasets with discrete and continuous variables.
  • Users can incorporate prior knowledge via a structural constraint interface.

Main Results:

  • BNW generates an interactive network model after structure learning.
  • The platform facilitates the understanding of relationships between network variables.
  • Users can generate testable hypotheses from the learned network models.

Conclusions:

  • BNW is a comprehensive platform for network modeling of biological data.
  • It supports hybrid datasets and prior knowledge integration.
  • BNW empowers users to explore complex biological relationships and formulate hypotheses.