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In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
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Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...

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Related Experiment Video

Updated: May 8, 2026

Ultrasound Cyclo Plasty in Eyes with Glaucoma

Ultrasound Cyclo Plasty in Eyes with Glaucoma

Published on: January 26, 2018

Eye drop instillation technique in patients with glaucoma.

A J Tatham¹, U Sarodia, F Gatrad

¹Department of Ophthalmology, University Hospital Leicester, Leicester, Leicestershire, UK.

Eye (London, England)

|August 24, 2013

Summary

Most glaucoma patients struggle with correct eye drop instillation. Proper training significantly improves technique, highlighting the need for routine assessment during glaucoma examinations.

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Ocular Therapeutic Delivery and Advanced Tissue Retrieval in Adult Rats

Ocular Therapeutic Delivery and Advanced Tissue Retrieval in Adult Rats

Published on: May 23, 2025

Area of Science:

Ophthalmology
Patient Education
Glaucoma Management

Background:

Glaucoma management relies heavily on topical medications.
Correct eye drop instillation is crucial for treatment efficacy.
Many patients exhibit suboptimal eye drop instillation techniques.

Purpose of the Study:

To evaluate the technique of eye drop instillation in glaucoma patients.
To identify factors associated with correct eye drop instillation.

Main Methods:

A cross-sectional observational study involving 85 glaucoma patients demonstrating eye drop instillation.
Assessment of technique by masked graders.
Logistic regression analysis to identify factors influencing technique.

Main Results:

Over half (54.1%) of patients demonstrated poor eye drop technique.
Key errors included missing the eye, touching the eye/conjunctiva with the bottle, and touching eyelids/lashes.
Previous instruction on technique was strongly associated with good technique (adjusted OR=8.17).
Increasing age was associated with poorer technique (adjusted OR=0.95).

Conclusions:

Patient education on eye drop instillation technique is significantly linked to correct administration.
Assessing a patient's ability to correctly instill eye drops should be a standard part of glaucoma care.