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FITC-quencher based caspase 3-activatable nanoprobes for effectively sensing caspase 3 in vitro and in cells
Anming Tang1, Bin Mei, Weijuan Wang
1CAS Key Laboratory of Soft Matter Chemistry, Department of Chemistry, University of Science and Technology of China, 96 Jinzhai Road, Hefei, Anhui 230026, China. gliang@ustc.edu.cn.
Nanoscale
|August 24, 2013
Abstract:
By employing fluorescence resonance energy transfer (FRET) quenching, we rationally designed two new FITC-quencher based nanoprobes for effectively sensing caspase 3 (Casp3) in vitro and in cells. Our nanoprobes hold promise for assessing the chemotherapeutic effect of cancer treatment.

