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Related Concept Videos

Peripheral Artery Disease III: Interprofessional Care01:27

Peripheral Artery Disease III: Interprofessional Care

Peripheral Artery Disease (PAD) is characterized by narrowed arteries that diminish blood flow to the extremities. Effective management of PAD requires an interprofessional approach involving various healthcare professionals. The critical aspects of interprofessional care for PAD patients focus on risk factor modification, drug therapy, exercise therapy, nutrition therapy, critical limb ischemia care, and interventional radiology and surgical procedures.The primary treatment goal for PAD...
Exercise Stress Test01:26

Exercise Stress Test

Introduction
Exercise stress testing, commonly known as a treadmill test, is a noninvasive procedure used to evaluate cardiovascular function and diagnose heart conditions.
Definition
An exercise stress test measures the heart's response to exertion using a treadmill or stationary bicycle. Chest electrodes record the heart's electrical activity through an ECG, and blood pressure is monitored regularly.
Purposes

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Updated: May 8, 2026

Computerized Dynamic Posturography for Postural Control Assessment in Patients with Intermittent Claudication
14:52

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Published on: December 11, 2013

Supervised exercise therapy versus non-supervised exercise therapy for intermittent claudication.

Hugo J P Fokkenrood1, Bianca L W Bendermacher, Gert Jan Lauret

  • 1Department of Vascular Surgery, Catharina Hospital, Michelangelolaan 2, Eindhoven, Netherlands, 5623 EJ.

The Cochrane Database of Systematic Reviews
|August 24, 2013
PubMed
Summary
This summary is machine-generated.

Supervised exercise therapy (SET) significantly improves walking distance for peripheral arterial disease (PAD) patients compared to non-supervised programs. While beneficial for treadmill walking, its impact on quality of life requires further investigation.

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Area of Science:

  • Vascular Medicine
  • Rehabilitation Science
  • Exercise Physiology

Background:

  • Supervised exercise therapy (SET) offers significant benefits for peripheral arterial disease (PAD) patients experiencing leg pain.
  • Implementing SET in daily practice faces challenges, necessitating updated reviews of its efficacy.

Purpose of the Study:

  • To evaluate the effects of supervised versus non-supervised exercise therapy on maximal walking time or distance in individuals with intermittent claudication.
  • To provide an updated overview of randomized clinical trials comparing different exercise modalities for PAD.

Main Methods:

  • Systematic review and meta-analysis of randomized clinical trials comparing SET with non-supervised exercise programs.
  • Searched multiple databases and handsearched references for relevant studies, with no language restrictions.
  • Extracted data on walking distance, pain-free walking distance, and quality of life (SF-36), calculating effect sizes using a fixed-effect model.

Main Results:

  • Fourteen studies with 1002 participants with PAD were included, with moderate to good trial quality.
  • SET demonstrated statistically significant improvements in maximal treadmill walking distance compared to non-supervised regimens (effect size 0.69 at 3 months, 0.48 at 6 months).
  • SET benefits for maximal and pain-free walking distances persisted at 12 months, but no significant impact on quality of life was observed.

Conclusions:

  • Supervised exercise therapy provides statistically significant benefits for treadmill walking distance in patients with intermittent claudication.
  • The clinical relevance of these improvements requires further demonstration, with a need for studies on quality of life and other functional outcomes.
  • Vascular professionals should ensure SET is accessible to all patients diagnosed with intermittent claudication.