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14:52
Computerized Dynamic Posturography for Postural Control Assessment in Patients with Intermittent Claudication
Published on: December 11, 2013
Physiology in medicine: peripheral arterial disease
Matthew D Muller1, Amy B Reed, Urs A Leuenberger
1Pennsylvania State University College of Medicine, Penn State Hershey Heart and Vascular Institute, Hershey, Pennsylvania.
Journal of Applied Physiology (Bethesda, Md. : 1985)
|August 24, 2013
Summary
Peripheral arterial disease (PAD) causes leg pain during exercise due to atherosclerosis. Understanding PAD
Area of Science:
- Physiology
- Pathophysiology
- Medical Science
Background:
- Peripheral arterial disease (PAD) is a complex atherosclerotic condition.
- PAD frequently coexists with hypertension, diabetes, dyslipidemia, smoking, and inactivity.
- Patients with PAD face elevated risks of myocardial infarction, stroke, and mortality.
Purpose of the Study:
- To enhance the physiological understanding of PAD pathogenesis.
- To review current and potential treatment options for PAD.
- To address the complex multifactorial nature of PAD.
Main Methods:
- This review synthesizes current physiological and medical knowledge on PAD.
- It examines the interplay of comorbid conditions in PAD.
- Literature review focusing on pathogenesis and therapeutic strategies.
Main Results:
- PAD pathophysiology involves multiple organ systems and complex interactions.
- Comorbidities significantly influence PAD development and progression.
- Understanding these complexities is crucial for effective management.
Conclusions:
- A comprehensive physiological understanding is essential for improving PAD treatment.
- Addressing PAD requires a multifactorial approach considering its associated conditions.
- Further research into PAD pathogenesis can lead to better patient outcomes.
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