Related Experiment Video
Updated: May 8, 2026

04:59
Rotating the Intraocular Lens to Prevent Posterior Capsular Opacification in Cataract Surgeries
Published on: July 7, 2023
Intraocular pressure fluctuation during microincision vitrectomy with constellation vision system.
Yoshimi Sugiura1, Fumiki Okamoto, Yoshifumi Okamoto
1Department of Ophthalmology, Faculty of Medicine, University of Tsukuba, Ibaraki, Japan.
American Journal of Ophthalmology
|August 27, 2013
Summary
The Alcon Constellation Vision System's intraocular pressure (IOP) control effectively minimizes IOP fluctuations during vitrectomy. Both 23- and 25-gauge systems showed similar IOP stability with this control engaged.
Area of Science:
- Ophthalmology
- Surgical Technology
- Biomedical Engineering
Background:
- Intraocular pressure (IOP) fluctuations during vitrectomy can pose risks.
- Understanding these fluctuations is crucial for surgical safety and patient outcomes.
Purpose of the Study:
- To evaluate intraocular pressure (IOP) variations during specific maneuvers with the Alcon Constellation Vision System.
- To assess the efficacy of the IOP control feature in mitigating these fluctuations.
Main Methods:
- Experimental laboratory investigation using porcine eyes.
- Performed 23- and 25-gauge vitrectomy in vitreous cutting, aspiration, and scleral compression modes.
- Measured IOP with the IOP control setting both on and off.
Main Results:
- The IOP control system significantly attenuated IOP drops during vitreous cutting and aspiration.
- Without IOP control, aspiration led to severe IOP depression (down to 2.2 mm Hg).
- Scleral compression caused rapid IOP spikes (70-100 mm Hg) regardless of IOP control status.
Conclusions:
- The IOP control system effectively reduces intraocular pressure fluctuations during vitrectomy.
- No significant difference in IOP fluctuation was observed between 23-gauge and 25-gauge vitrectomy systems.
Related Concept Videos
Glaucoma: Overview
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
Angle Closure Glaucoma: Treatment
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
Open Angle Glaucoma: Treatment
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
