Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

The Tumor Microenvironment02:17

The Tumor Microenvironment

Every normal cell or tissue is embedded in a complex local environment called stroma, consisting of different cell types, a basal membrane, and blood vessels. As normal cells mutate and develop into cancer cells, their local environment also changes to allow cancer progression. The tumor microenvironment (TME) consists of a complex cellular matrix of stromal cells and the developing tumor. The cross-talk between cancer cells and surrounding stromal cells is critical to disrupt normal tissue...
The Tumor Microenvironment02:17

The Tumor Microenvironment

Every normal cell or tissue is embedded in a complex local environment called stroma, consisting of different cell types, a basal membrane, and blood vessels. As normal cells mutate and develop into cancer cells, their local environment also changes to allow cancer progression. The tumor microenvironment (TME) consists of a complex cellular matrix of stromal cells and the developing tumor. The cross-talk between cancer cells and surrounding stromal cells is critical to disrupt normal tissue...
Adaptive Mechanisms in Cancer Cells02:53

Adaptive Mechanisms in Cancer Cells

Cancer cells accumulate genetic changes at an abnormally rapid rate due to the defects in the DNA repair mechanisms. From an evolutionary perspective, such genetic instability is advantageous for cancer development. Mutant cell lines accumulate a series of beneficial mutations that contribute to their progression into cancer.
Some of the advantages that cancer cells have on normal cells include - enhanced ability to divide without terminally differentiating, induce new blood vessel formation,...
Adaptive Mechanisms in Cancer Cells02:53

Adaptive Mechanisms in Cancer Cells

Cancer cells accumulate genetic changes at an abnormally rapid rate due to the defects in the DNA repair mechanisms. From an evolutionary perspective, such genetic instability is advantageous for cancer development. Mutant cell lines accumulate a series of beneficial mutations that contribute to their progression into cancer.
Some of the advantages that cancer cells have on normal cells include - enhanced ability to divide without terminally differentiating, induce new blood vessel formation,...
What is Cancer?02:12

What is Cancer?

Cells and tissues must meticulously coordinate their activities for the normal functioning of the human body. Therefore, they exhibit socially responsible behavior - resting, growing, dividing, differentiating, or dying - for the organism’s benefit. Cancer arises when cells divide uncontrollably and invade other tissues or organs.
Although people have known about cancer for centuries, it was only in 1761 that Giovanni Morgagni of Padua performed a detailed autopsy of patients who died from...
Cancer Stem Cells and Tumor Maintenance02:40

Cancer Stem Cells and Tumor Maintenance

Early diagnosis and treatment can often cure cancer. However, even with treatment, residual cells called cancer stem cells (CSC) might remain, often causing tumor recurrence. These cancer stem cells possess the potential for self-renewal and multi-lineage differentiation and are often responsible for the therapeutic resistance displayed in most cancers.
Cancer stem cells are thought to originate from tissue-specific normal stem cells or progenitor cells. The normal stem cells usually reside in...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

In vivo reduction of Treg expansion in rodent helminth-malaria coinfection.

Parasites & vectors·2026
Same author

When effective anticancer therapies are, in fact, destabilizing the tumor's Group Phenotypic Composition.

NPJ precision oncology·2026
Same author

Advances in mosquito-borne disease surveillance using machine learning.

New microbes and new infections·2026
Same author

Surveillance of Zoonotic Pathogens in Small Mammals Across Forests With Different Levels of Anthropization in Eastern France.

Transboundary and emerging diseases·2026
Same author

Evidence of SARS-CoV-2 Exposure in Rodents from Rural Localities in the Yucatan Peninsula, Mexico.

Viruses·2026
Same author

Seroprevalence of endemic and emergent coronaviruses among SARS-COV-2 patients and healthcare workers in Abidjan, Côte d'Ivoire.

BMC infectious diseases·2026
Same journal

Can habitat modification in the native range promote invasion?

Trends in ecology & evolution·2026
Same journal

The host-microbiome dimension of ecological regime shifts.

Trends in ecology & evolution·2026
Same journal

The emerging field of wild animal welfare science.

Trends in ecology & evolution·2026
Same journal

Integrating nutritional mutualists into the evolution of defense.

Trends in ecology & evolution·2026
Same journal

Formation of three great Asian plateaus, climate change, and biodiversity: (Trends Ecol. Evol. 40, 970-982; 2025).

Trends in ecology & evolution·2026
Same journal

Digital twins as a tool for ecosystem research.

Trends in ecology & evolution·2026
See all related articles

Related Experiment Video

Updated: May 8, 2026

Deficient Pms2, ERCC1, Ku86, CcOI in Field Defects During Progression to Colon Cancer
28:15

Deficient Pms2, ERCC1, Ku86, CcOI in Field Defects During Progression to Colon Cancer

Published on: July 28, 2010

Cancer: a missing link in ecosystem functioning?

Marion Vittecoq1, Benjamin Roche, Simon P Daoust

  • 1Maladies Infectieuses et Vecteurs: Écologie, Génétique, Évolution et Contrôle (MIVEGEC), Unité Mixte de Recherche (UMR), Institut de Recherche pour le Développement (IRD)/Centre National de la Recherche Scientifique (CNRS)/Unité Mixte 5290, 911 Avenue Agropolis, BP 64501, 34394 Montpellier CEDEX 5, France; Centre de Recherche de la Tour du Valat, le Sambuc, 13200, Arles, France; Centre for Ecological and Evolutionary Cancer Research (CREEC), 95 rue de la Galera, 34090, Montpellier, France.

Trends in Ecology & Evolution
|August 27, 2013
PubMed
Summary
This summary is machine-generated.

Cancer impacts wildlife ecology by affecting competition, pathogen susceptibility, and predator vulnerability. Understanding these oncogenic phenomena is crucial for ecological and evolutionary research in wild populations.

Keywords:
biotic interactionscancerecosystemtumorwildlife

More Related Videos

Linking Predation Risk, Herbivore Physiological Stress and Microbial Decomposition of Plant Litter
10:20

Linking Predation Risk, Herbivore Physiological Stress and Microbial Decomposition of Plant Litter

Published on: March 12, 2013

A Mimic of the Tumor Microenvironment: A Simple Method for Generating Enriched Cell Populations and Investigating Intercellular Communication
09:52

A Mimic of the Tumor Microenvironment: A Simple Method for Generating Enriched Cell Populations and Investigating Intercellular Communication

Published on: September 20, 2016

Related Experiment Videos

Last Updated: May 8, 2026

Deficient Pms2, ERCC1, Ku86, CcOI in Field Defects During Progression to Colon Cancer
28:15

Deficient Pms2, ERCC1, Ku86, CcOI in Field Defects During Progression to Colon Cancer

Published on: July 28, 2010

Linking Predation Risk, Herbivore Physiological Stress and Microbial Decomposition of Plant Litter
10:20

Linking Predation Risk, Herbivore Physiological Stress and Microbial Decomposition of Plant Litter

Published on: March 12, 2013

A Mimic of the Tumor Microenvironment: A Simple Method for Generating Enriched Cell Populations and Investigating Intercellular Communication
09:52

A Mimic of the Tumor Microenvironment: A Simple Method for Generating Enriched Cell Populations and Investigating Intercellular Communication

Published on: September 20, 2016

Area of Science:

  • Ecology
  • Evolutionary Biology
  • Wildlife Health

Background:

  • Cancer affects most animal species, influencing individual fitness before death.
  • Ecological impacts of cancer are often overlooked in ecosystem models.
  • Oncogenic phenomena can alter biotic interactions and population dynamics.

Purpose of the Study:

  • To explore how cancer influences ecological processes in wildlife.
  • To highlight the ecological significance of oncogenic phenomena.
  • To stimulate research on cancer's role in ecosystems.

Main Methods:

  • Review of ecological impacts of cancer across metazoan species.
  • Analysis of how precancerous and metastatic cancers affect ecological interactions.
  • Conceptual framework for integrating cancer into ecological studies.

Main Results:

  • Oncogenic phenomena can significantly affect individual traits like competition and dispersal.
  • Cancer can alter susceptibility to pathogens and vulnerability to predators.
  • Ecological consequences of cancer can be predictable despite its complexity.

Conclusions:

  • Cancer has significant, often predictable, ecological consequences in wildlife.
  • Integrating cancer into ecological models is essential for a comprehensive understanding of ecosystems.
  • Further research is needed to elucidate the ecological and evolutionary significance of cancer in wild populations.