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Published on: April 28, 2013
Necrotizing fasciitis in patients who underwent renal transplantation
1Department of Medicine, Division of Nephrology, Taichung Veterans General Hospital and Department of Life Science, Tunghai University, Taichung, Taiwan.
Abstract:
A 48-year-old man receiving renal transplantation was admitted due to bacterial pneumonia. Unfortunately, he developed septic shock due to Escherichia coli-related necrotizing fasciitis (NF). To date, there have only been 11 such cases reported in the literature and this is the first case caused by E coli. An analysis of all 12 cases showed 83% of patients had the infection in the extremities, 27.3% of pathogens was Streptococcus pyogenes, 50% of patients had shock, but the mortality rate (16.7%) was no greater than that seen in non-renal transplant patients with NF. The elderly had higher mortality (P = .085) and patients taking mycophenoic acid had a higher risk of death (P = .039).
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